Product Name: 3-[2-(2-Aminoethylamino)Ethylamino]Propyl-Trimethoxysilane
Chemical Family: Organosilane compound
Synonyms: N-(2-aminoethyl)-3-aminopropyltrimethoxysilane, Triaminopropylsilane
CAS Number: 1760-24-3
Recommended Use: Surface modifier, adhesion promoter for silicones, epoxies, and urethanes
Supplier: Manufacturer or authorized distributor contact details and emergency phone indicated on packaging label
Emergency Contact: CHEMTREC or local poison control center for hazardous incidents
GHS Classification: Skin corrosion (Category 1B), Eye damage (Category 1), Acute toxicity oral (Category 4), Acute aquatic toxicity (Category 3)
Signal Word: Danger
Pictograms: Corrosive, Exclamation Mark, Environment
Hazard Statements: Causes severe skin burns and eye damage; harmful if swallowed; causes serious eye damage; harmful to aquatic life
Precautionary Statements: Wear protective gloves, eye protection, and face shield; wash all exposed areas after handling; avoid release to environment; obtain medical attention if accidents occur
Specific Hazards: Vapors and mists cause strong irritation to eyes, nose, and throat; chronic exposure can produce headache, dizziness, and skin disorders
Chemical Name: 3-[2-(2-Aminoethylamino)Ethylamino]Propyl-Trimethoxysilane
Common Name: Triaminopropylsilane
CAS Number: 1760-24-3
Weight Percent: >98% (purity as supplied)
Impurities: Methanol <0.5% (can form upon hydrolysis), traces of siloxanes possible
Additives: None
Inhalation: Remove person to fresh air; keep at rest; seek medical attention for respiratory symptoms or difficulty breathing
Skin Contact: Immediately flush with copious water and soap for at least 15 minutes; remove contaminated clothing and shoes; medical attention required for burns, persistent irritation, or systemic effects
Eye Contact: Rinse under running water for at least 20 minutes, lifting eyelids frequently; remove contact lenses if easy; seek urgent medical care for pain or vision change
Ingestion: Rinse mouth; do not induce vomiting unless directed by medical professionals; provide water to dilute; seek emergency medical help
Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, water spray (avoid water jet which can spread the substance)
Hazardous Combustion Products: Silicon oxides, nitrogen oxides, carbon oxides, methanol, toxic fumes
Fire Fighting Procedures: Firefighters use self-contained breathing apparatus and full protective clothing; cool tanks with water spray from a safe distance; prevent firewater runoff entering drains
Specific Hazards in Fire: Vapors may form explosive mixtures with air; thermal decomposition can release hazardous gases
Personal Precautions: Restrict access, ventilate area, evacuate unnecessary personnel, avoid inhalation/skin contact, wear suitable PPE (chemical resistant gloves, splash goggles, face shield, protective clothing)
Environmental Precautions: Prevent entry into sewers, groundwater, or surface water; report to authorities if large scale environmental contamination occurs
Clean-up Methods: Contain spillage with absorbent material (sand, vermiculite); shovel into closed containers for disposal; wash contaminated area with detergent and copious water; ventilate area well; dispose according to regulations
Handling: Handle in well-ventilated places, avoid breathing vapors/mist; never eat, drink, or smoke while using; wash thoroughly after use; handle in closed systems where possible; keep container tightly sealed
Storage Conditions: Keep in original container in cool, dry, well-ventilated place; store away from incompatible materials like strong acids, oxidizers, and moisture; avoid extreme temperatures and direct sunlight
Further Notes: Drums should be grounded or bonded to prevent electrostatic discharge during transfer processes; segregation required from food and animal feedstuffs
Incompatibility: Reacts with water or humid air forming methanol; incompatible with alkalis, strong acids, oxidizing agents
Engineering Controls: Use only in effective fume hoods or with local exhaust ventilation; maintain eyewash stations and emergency showers nearby
Personal Protective Equipment: Gloves (nitrile or neoprene), full-sleeve lab coat or apron, chemical splash goggles and face shield; use respiratory protection (NIOSH/MSHA approved respirator) for excessive vapor, in poorly ventilated areas
Occupational Exposure Limit: No specific limits set for compound, monitor for methanol byproduct: ACGIH TLV (skin) TWA 200 ppm; ensure levels below established OELs for decomposition products
Hygiene Practices: Remove contaminated clothing, launder before reuse, do not take work clothing home
Appearance: Clear to pale yellow liquid
Odor: Amine-like, strong and unpleasant
Odor Threshold: Not available
pH: Strongly basic aqueous solution
Melting/Freezing Point: <-20°C
Boiling Point/Range: 277°C at atmospheric pressure
Flash Point: 114°C (closed cup)
Evaporation Rate: Not rapid, moderate evaporation
Flammability: Flammable vapor/air mixtures may form above flash point
Upper/Lower Explosion Limits: Not available for compound; methanol vapor 6-36% vol.
Vapor Pressure: <1 mm Hg at 25°C
Vapor Density: >1 (air=1)
Relative Density: 1.04 g/cm³ at 25°C
Solubility: Reacts with water, soluble in alcohols and some polar solvents
Partition Coefficient n-octanol/water: Not determined
Auto-Ignition Temperature: 360°C
Decomposition Temperature: Decomposes above 200°C
Viscosity: 25 cP at 25°C
Molecular Formula: C10H27N3O3Si
Molecular Weight: 265.43 g/mol
Chemical Stability: Stable in sealed containers; hydrolyzes rapidly in humid conditions, releasing methanol
Possible Hazardous Reactions: Polymerizes on contact with water or moisture, forming siloxane network and liberating methanol
Reactivity: Reacts strongly with acids, oxidizers, water
Conditions to Avoid: Moisture, prolonged heating, contact with incompatible substances
Hazardous Decomposition Products: Silica, silicon oxides, nitrogen oxides, carbon monoxide and dioxide, methanol
Incompatible Materials: Strong acids, bases, oxidizing agents, water (hydrolysis risk)
Likely Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Oral LD50 (rat): 2295 mg/kg; Dermal LD50 (rabbit): >2000 mg/kg; irritation and corrosive damage expected
Skin Corrosion/Irritation: Severe corrosive to skin, may lead to burns or ulceration on prolonged contact
Serious Eye Damage/Irritation: Severe risk to eyes, irreversible damage or blindness possible
Inhalation Effects: Irritates nose, throat, respiratory system; high vapor concentrations may cause shortness of breath, headache, or nausea
Sensitization: Not classified as sensitizer, but repeated exposure may increase sensitivity
Chronic Effects: Prolonged or repeated exposure may cause dermatitis, allergic skin response, possible effects on liver or kidneys
Carcinogenicity/Mutagenicity: No IARC, OSHA or NTP listing; no evidence of germ cell mutagenicity
Other Health Hazards: Methanol from hydrolysis can cause systemic toxicity including CNS depression, visual impairment, acidosis
Toxicity to Aquatic Life: Harmful to aquatic organisms; possible adverse effects on aquatic environments from direct release
Persistence and Degradability: Hydrolyzes rapidly to silanol and methanol in water; intermediate products degrade further
Bioaccumulative Potential: No evidence of bioaccumulation; hydrolysis products and methanol do not persist
Mobility in Soil: Mobile under wet conditions but reacts to form insoluble siloxanes; migration potential influenced by soil pH, moisture
Other Environmental Hazards: Avoid uncontrolled release; substance and hydrolysis products may disrupt wastewater treatment checks
Ozone Depletion, PBT/vPvB Assessment: Not classified for these effects under current regulations
Waste Disposal: Dispose of product in accordance with federal, state, and local environmental regulations; incineration at controlled facilities recommended
Contaminated Packaging: Triple rinse containers, offer for recycling or puncture and dispose of as hazardous waste
Precautions for Disposal: Do not discharge to drains or open environment; prevent spills or leaks during handling and transport; use caution if burning due to risk of toxic byproducts
Permitted Treatment Methods: Approved chemical or physical waste treatment; consultation with licensed waste disposal contractor necessary
UN Number: UN 2735
Proper Shipping Name: Amines, liquid, corrosive, n.o.s. (contains: 3-[2-(2-Aminoethylamino)Ethylamino]Propyl-Trimethoxysilane)
Transport Hazard Class: Class 8 (Corrosive substance)
Packing Group: II
Label: Corrosive
Marine Pollutant: Not regulated as marine pollutant per IMDG, but caution required for bulk shipments
Special Precautions: Carry as tightly sealed containers; keep away from incompatible substances; comply with national and international regulations covering hazardous substances
Additional Transport Notes: Emergency instructions and contact numbers accompany shipment; ensure proper training for personnel involved in loading and unloading
OSHA Hazard Communication: Corrosive, hazardous; requires labeling under hazard communication rules
TSCA Status: Listed on TSCA Inventory
REACH Status: Registered substance within European Union, registration number available from supplier
SARA Title III: Not subject to SARA 302, SARA 313 reporting; subject to SARA 311/312: Acute health hazard
California Proposition 65: Methanol generated upon hydrolysis listed as reproductive toxicant; product may release small quantities upon storage or use
Canadian DSL/NDSL: Listed on Canadian Domestic Substances List
Other International Regulations: Complies with chemical control regulations in Japan, Australia, Korea, China
Labeling Requirements: Conforms to GHS and regional requirements; hazard pictograms, signal words, and precautionary statements required on containers at all times
