Product Name: 3-Chloroisobutylmethyldimethoxysilane
Chemical Formula: C7H17ClO2Si
CAS Number: 31001-77-1
Synonyms: Chloromethylisobutyldimethoxysilane
Manufacturer: Name, address, and emergency contact information to be filled as per supply source
Recommended Use: Surface modification, specialty silane coupling agent for various industrial processes
Restrictions: Intended for use by trained professionals in industrial or laboratory settings
Supplier Contact: Insert distributor or supplier details for traceability and emergency consultation
Classification: Skin corrosion/irritation (Category 2); Eye damage/irritation (Category 1); Acute toxicity—oral (Category 4); Specific target organ toxicity—single exposure (Category 3)
Pictogram: GHS corrosion, exclamation mark
Signal Word: Danger
Hazard Statements: Causes serious eye damage; causes skin irritation; harmful if swallowed; may cause respiratory irritation
Precautionary Statements: Wash thoroughly after handling; wear eye/face protection, protective gloves and clothing; avoid breathing vapors, use only outdoors or in a well-ventilated area
Other Hazards: Reacts with water to form methanol, vapor may be irritating to mucous membranes
Chemical Name: 3-Chloroisobutylmethyldimethoxysilane
Concentration: >95%
Other Components: Impurities and stabilizing agents may be present at low levels as part of the manufacturing process, but no other hazardous ingredients above regulatory thresholds
CAS Number: 31001-77-1
Formula: C7H17ClO2Si
Inhalation: Remove individual to fresh air rapidly, keep at rest in a position comfortable for breathing, seek immediate medical attention if symptoms persist (dizziness, headache, respiratory distress)
Skin Contact: Remove contaminated clothing, rinse skin thoroughly with water and mild soap for at least 15 minutes, seek medical attention if skin irritation develops or persists
Eye Contact: Rinse cautiously with water for at least 15 minutes, lifting eyelids occasionally, seek prompt medical attention—immediate action is critical
Ingestion: Do not induce vomiting, rinse mouth with water, never give anything by mouth to an unconscious person, call poison control or seek immediate medical help
Most Important Symptoms: Burning sensation, redness, pain and swelling at contact sites on skin and eyes, respiratory discomfort, gastrointestinal distress if ingested
Notes for Physicians: Treat symptomatically, monitor for delayed pulmonary effects, supportive care for eye and respiratory irritation
Suitable Extinguishing Media: Use dry chemical, foam or carbon dioxide; water spray may be used to cool containers but avoid direct water as hydrolysis may release flammable methanol
Specific Hazards from Fire: Toxic and corrosive gases produced such as hydrogen chloride, silicon oxides, and formaldehyde; exothermic reaction with water, flammable vapor hazard
Protective Equipment for Firefighters: Full protective gear including self-contained breathing apparatus; stay upwind, avoid breathing fumes
Additional Advice: Containers may explode in heat of fire, cool nearby drums with water spray from safe location; evacuate area if large-scale release is possible
Personal Precautions: Evacuate non-essential personnel, equip responders with proper chemical-resistant gloves, eye protection, and respiratory protection
Environmental Precautions: Prevent entry into drains, surface water or soil; inform relevant authorities if product contaminates environment
Containment and Cleanup: Absorb spill with inert material (dry sand, earth), collect into secure chemical waste containers with minimal dust formation, ventilate area; neutralize trace residues with dilute acid only after bulk removal
Methods for Cleaning Up: Clean spill site with water and detergent after removal, ensure appropriate waste disposal; do not use combustible material such as sawdust
Safe Handling Advice: Ensure good general ventilation or local exhaust at place of use; avoid inhalation of vapors, contact with skin or eyes, never eat, drink or smoke during handling
Storage Conditions: Store in tightly closed containers, in a cool, dry, well-ventilated area away from water, acids, strong oxidizers and bases; protect from moisture due to reactivity with water
Incompatible Materials: Avoid storing with strong acids and oxidizing agents; do not allow contact with water or alcohols; incompatible with metal containers prone to corrosion
Special Requirements: Keep away from food, drink and animal feed; segregate from non-compatible chemicals; label storage area clearly
Control Parameters: No specific occupational exposure limits established; monitor workplace air for vapor accumulation
Engineering Controls: Use closed processes, local exhaust ventilation or other engineering controls to keep airborne levels below recommended exposure limits
Personal Protective Equipment: Chemical-resistant gloves (nitrile, neoprene), goggles or face shield, protective clothing (long sleeves, chemical apron); in case of inadequate ventilation, use appropriate respirator (organic vapor filter)
Hygiene Measures: Wash hands thoroughly after handling, remove contaminated clothing before entering communal areas, never reuse unwashed protective gear
Appearance: Colorless to slightly yellow liquid
Odor: Pungent, irritating odor
Melting Point/Range: Not determined due to liquid state
Boiling Point/Range: Approximately 170°C (338°F)
Flash Point: 68°C (154°F) (closed cup)
Flammability: Combustible liquid
Vapor Pressure: 2 mm Hg at 20°C
Vapor Density: 4.9 (air = 1)
Solubility: Reacts with water, hydrolyzes forming silanols and methanol
Partition Coefficient (log Kow): Not available
Autoignition Temperature: Not determined
Decomposition Temperature: Not determined
Viscosity: 1-2 cP at 25°C
Chemical Stability: Stable under recommended storage conditions without moisture
Possibility of Hazardous Reactions: Hydrolyzes rapidly with water, generating methanol and siloxanes; forms flammable and toxic gases when exposed to acids, bases, or heat
Conditions to Avoid: Heat, flame, sources of ignition, humidity/moisture, incompatible substances such as strong oxidizing acids
Incompatible Materials: Water, strong acids, bases, oxidizers, materials sensitive to methanol
Hazardous Decomposition Products: Hydrogen chloride, silicon oxides, carbon oxides, methanol, formaldehyde
Routes of Exposure: Inhalation, skin absorption, eye contact, ingestion
Acute Toxicity: Harmful if swallowed (estimated oral LD50: 500-2000 mg/kg, rat); causes skin and serious eye irritation; inhalation exposure can lead to respiratory irritation
Chronic Effects: Prolonged or repeated exposure may cause dermatitis, sensitization, or delayed respiratory symptoms
Symptoms: Redness, blistering, burns on skin, watering and pain in eyes, headache, dizziness, drowsiness following methanol formation with hydrolysis
Carcinogenicity: Not classified as a known carcinogen by IARC/NTP/OSHA
Other Health Effects: Methanol formed by hydrolysis can cause blindness, central nervous system depression
Ecotoxicity: Toxic to aquatic organisms due to hydrolysis products such as methanol and silanols; acute and chronic effects likely in sensitive species
Persistence and Degradability: Readily hydrolyzes in aquatic environment; parent material not considered persistent but breakdown products remain hazardous
Bioaccumulation: Expected to be low for parent compound; some metabolites may bioaccumulate in food chain
Mobility in Soil: Mobile in soil due to water reactivity; migration to groundwater possible if released in large quantities
Other Adverse Effects: High vapor pressure may facilitate air transport and deposition at distance from site of original release
Waste Treatment Methods: Dispose of product, contaminated materials, and packaging in accordance with all local, regional, national and international regulations
Disposal of Product: Incinerate only in proper chemical incinerators equipped with afterburner and scrubber to capture silicon and hydrochloric acid residues; small amounts may be diluted and neutralized before disposal in chemical landfill
Disposal of Packaging: Completely empty container, triple rinse with appropriate solvent, then puncture and dispose through licensed facility
Precautions for Disposal: Avoid disposal through sewage system; do not allow entrance into natural waterways
UN Number: UN 1993
UN Proper Shipping Name: Flammable liquid, n.o.s. (contains 3-Chloroisobutylmethyldimethoxysilane)
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: III
Special Precautions: Avoid shipment with food and feeds; protect from heat, moisture, and incompatible cargo
Marine Pollutant: Yes
Transport Labels: Flammable Liquid, Corrosive (if required by destination regulations)
Global Inventory Status: Check chemical is listed or exempted on TSCA (USA), EINECS (EU), DSL (Canada), IECSC (China), ENCS (Japan), and AICS (Australia) inventories
U.S. Regulations: Subject to OSHA Hazard Communication Standard, classified as hazardous; SARA Title III (Sections 311/312: acute health, fire hazards); RCRA hazardous waste
EU Regulations: Classified as hazardous under CLP Regulation (EC) No. 1272/2008
Other Regulatory Information: Restrictions may apply to manufacture, import and use in specific regions; safety data and chemical safety assessment required for supply chain participants
Labeling Requirements: Ensure correct pictograms, signal word, hazard and precautionary statements conform to regulatory jurisdiction
