Chemical Name: 3-Glycidyloxypropylmethyldiethoxysilane
Synonyms: Glycidoxypropylmethyldiethoxysilane, Epoxy functional silane
CAS Number: 2897-60-1
Product Use: Adhesion promoter, crosslinking agent, used in surface treatments, sealants, coatings, and adhesives
Supplier/Manufacturer Details: Manufacturer address and contact available upon request
Emergency Telephone: National Poison Control Center, manufacturer 24-hour number
Recommended Restrictions: For industrial and laboratory use only, not for food or drug applications
GHS Classification: Flammable liquid, skin irritant, eye irritant, skin sensitizer
Signal Word: Warning
Hazard Statements: Causes skin irritation, causes serious eye irritation, may cause allergic skin reaction, flammable liquid and vapor
Precautionary Statements: Avoid breathing vapors, use explosion-proof equipment, wear protective gloves and eye protection, wash thoroughly after handling, keep away from heat and ignition sources
Symptoms of Exposure: Redness, itching, swelling of skin, eye watering, stinging, respiratory irritation in poorly ventilated areas
Chemical Identity: 3-Glycidyloxypropylmethyldiethoxysilane
Chemical Formula: C13H28O5Si
Component Breakdown:
Inhalation: Remove person to fresh air, keep comfortable, seek medical attention if symptoms persist
Skin Contact: Wash area immediately with soap and water, remove contaminated clothing, seek medical advice if irritation or inflammation occurs
Eye Contact: Rinse eyes slowly with water for 15 minutes, lift eyelids occasionally, remove contact lenses if present and easy to do, call physician if irritation persists
Ingestion: Rinse mouth with water, do not induce vomiting, seek medical advice immediately
Indication of Immediate Medical Attention: Allergic reactions, severe irritation, respiratory distress require urgent care
Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical, carbon dioxide
Unsuitable Extinguishing Media: Direct water stream can scatter and spread fire
Special Hazards: Vapors may form explosive mixture with air, combustion may generate silica oxides, carbon oxides and other toxic fumes
Protective Equipment: Firefighters use self-contained breathing apparatus and full protective clothing
Advice for Firefighters: Cool unopened containers with water spray, avoid inhalation of combustion products, evacuate area if necessary
Personal Precautions: Evacuate unnecessary personnel, wear chemical-resistant gloves, goggles, and protective clothing
Environmental Precautions: Prevent spillage from entering sewers, waterways, or soil
Methods for Clean-up: Absorb with inert material (sand, earth), place in chemical waste container, ventilate area, clean surface thoroughly
Disposal: Dispose collected waste in accordance with local, regional, and national regulations
Safe Handling: Use in well-ventilated areas, avoid inhalation and skin contact, prevent static discharge by grounding handling equipment
Hygiene Measures: Wash hands after handling, do not eat, drink, or smoke in work areas
Storage Conditions: Store in tightly closed original container, keep in cool, dry, well-ventilated area away from heat, sparks, or open flame
Incompatible Materials: Strong acids, bases, oxidizing agents, moisture
Specific Uses: Used as coupling agent for organosilicon chemistry, not intended for consumer use
Engineering Controls: Provide adequate local ventilation, use explosion-proof electrical supplies, employ eyewash stations and emergency showers
Exposure Limits: Occupational exposure limits not established for this compound
Personal Protective Equipment: Protective gloves (nitrile or neoprene), safety goggles, long-sleeved laboratory coat, chemical-resistant apron if risk of splashing
Respiratory Protection: Wear approved respirator in absence of adequate ventilation, particularly during spill or high-concentration use
Environmental Controls: Avoid release to environment, capture vapors and prevent emission using filters or scrubbers when practical
Appearance: Colorless to pale yellow clear liquid
Odor: Mild, characteristic
Odor Threshold: Not available
pH: Not determined
Boiling Point: 285-290°C
Melting Point: Not determined
Flash Point: 110°C (closed cup)
Evaporation Rate: Not determined
Flammability: Flammable liquid
Vapor Pressure: <0.5 mmHg at 25°C
Vapor Density: Heavier than air
Relative Density: 1.03-1.07 g/cm³ (20°C)
Solubility: Reacts slowly with water, forms silanols and ethanol
Partition Coefficient (n-octanol/water): Not available
Autoignition Temperature: >200°C
Decomposition Temperature: Not determined
Viscosity: 3-7 mPa.s (25°C)
Chemical Stability: Stable under dry, normal conditions
Reactivity: Hydrolyzes in presence of water, releases ethanol
Hazardous Reactions: Contact with strong acids, bases, oxidizers may cause violent reaction
Conditions to Avoid: Heat, flame, ignition sources, exposure to moisture
Hazardous Decomposition Products: Carbon oxides, silicon oxides, ethanol under combustion or hydrolysis
Acute Toxicity: Oral LD50 (rat) estimated above 5000 mg/kg, low acute toxicity
Skin Corrosion/Irritation: Causes moderate skin irritation, risk of allergic reactions
Eye Damage/Irritation: Causes serious eye irritation
Respiratory Sensitization: May cause mild respiratory tract irritation, especially at high vapor concentrations
Germ Cell Mutagenicity: No evidence of mutagenic effects in animal studies
Carcinogenicity: Not classified by IARC, NTP, or OSHA
Reproductive Toxicity: No data indicating reproductive harm
Repeated Dose Toxicity: Prolonged or repeated skin contact may cause dermatitis
Symptoms: Redness, itching, blistering of skin, eye watering and pain, headache, nausea (due to ethanol release or high vapor)
Ecotoxicity: Harmful to aquatic life, especially if released in large amounts
Aquatic Toxicity: Data limited, but silane hydrolysis products and solvents can affect aquatic organisms
Persistence and Degradability: Undergoes hydrolysis in water, forms organosilicon compounds and ethanol, breakdown products partially biodegradable
Bioaccumulation Potential: Low, due to rapid hydrolysis and conversion to non-volatile species
Mobility in Soil: Moderate, converted to less mobile silanols by water
Other Adverse Effects: Avoid entry into surface water, drains, or soil, as environmental risk increases with quantity and frequency of spillage
Disposal Methods: Collect liquid in labeled container for hazardous chemical disposal, incinerate in permitted facility, do not pour down drains or sewers
Contaminated Packaging: Empty containers must be thoroughly cleaned before reuse or disposal, follow regulations for hazardous waste
Local/Regional Restrictions: Dispose according to environmental regulations in place for industrial chemical waste
Precautions: Do not reuse container for other chemicals or products, professional waste handler recommended
UN Number: UN 1993
Proper Shipping Name: Flammable Liquid, N.O.S. (contains 3-Glycidyloxypropylmethyldiethoxysilane)
Transport Hazard Class: 3 (Flammable Liquids)
Packing Group: III
ERG Code: 3L
Environmental Hazards: Not classified as marine pollutant at typical concentrations
Special Transport Precautions: Protect from physical damage, segregate from incompatible materials (acids, bases, oxidizers), keep away from heat sources, transport in original container with cap securely in place
OSHA Status: Considered hazardous by Occupational Safety and Health Administration
TSCA Status: Listed on Toxic Substances Control Act inventory
SARA Title III: Not listed for Section 302, not subject to Section 313 reporting
DSL/NDSL: Listed on Canadian Domestic Substances List
REACH Registration: Pre-registered or fully registered in accordance with EU requirements
California Proposition 65: Not listed as causing cancer, birth defects, or reproductive harm
Other Regulations: Comply with all federal, state, and local environmental control regulations
Chemical Safety Assessment: Has been carried out for uses described and supplied upon request
