Product Name: 3-Glycidyloxypropyltriethoxysilane
Synonyms: (3-Glycidyloxypropyl)triethoxysilane, GPTES, KH-560
CAS Number: 2602-34-8
Use: Coupling agent in adhesives, sealants, resins, glass fiber treatment, and surface modification
Supplier: Specialized chemical manufacturers and laboratory suppliers
Contact Information: Emergency phone numbers provided by the supplier, standard safety office lines for inquiries
GHS Classification: Causes skin irritation, causes eye irritation, may cause respiratory irritation, suspected of causing genetic defects
Pictogram: Exclamation mark, Health hazard
Signal Word: Warning
Hazard Statements: Irritates skin and eyes on contact, possible harm by inhalation, long exposure increases risk for genetic changes
Precautionary Statements: Wear protective gloves and eye protection, avoid inhaling vapors, wash thoroughly after handling, use in well ventilated areas
Chemical Name: 3-Glycidyloxypropyltriethoxysilane
CAS Number: 2602-34-8
Purity: 97% or higher (typical commercial grade)
Impurities: Small quantities of related organosilanes
Additives: No additives specified by suppliers
Inhalation: Move to fresh air right away, seek medical help if symptoms persist, avoid breathing further vapors
Skin Contact: Rinse with plenty of water for at least 15 minutes, remove any contaminated clothing, wash thoroughly with soap, seek medical attention for irritation
Eye Contact: Rinse with water for several minutes, keep eyes wide open, call a doctor if discomfort continues
Ingestion: Rinse mouth, do not induce vomiting, seek prompt medical care
Key Symptoms: Redness, itching, burning of skin and eyes, coughing, difficulty breathing in severe exposure
Suitable Extinguishing Media: Foam, dry chemical powder, carbon dioxide, do not use water stream directly
Hazardous Decomposition Products: Carbon oxides, silicon oxides, irritating vapors or gases might appear during a fire
Protective Equipment: Firefighters should wear full protective clothing and self-contained breathing apparatus
Special Procedures: Move containers away from fire area if it can be done without risk, cool containers with water spray
Flammability: Not highly flammable but vapors may form explosive mixtures with air in confined spaces
Personal Precautions: Avoid inhaling vapors or mist, ensure area is well-ventilated, wear suitable protective equipment
Environmental Precautions: Prevent entry into drains or waterways, contain spills using sand or inert absorbent
Clean-Up Methods: Use non-sparking tools, collect spillage in suitable containers for disposal, wash area with water after clean-up
Reporting: Notify proper authorities in case of large spills or contamination risk
Safe Handling: Use only with adequate ventilation, avoid contact with skin and eyes, do not breathe vapors, keep away from sources of ignition, use bonding/grounding for transferring large volumes
Storage Conditions: Store in tightly closed containers, away from heat, sparks, direct sunlight, and moisture, store at ambient temperature, ensure good ventilation in storage area
Incompatible Materials: Avoid contact with water, strong oxidizers, acids, alkalis, and materials that react with epoxides or silanes
Storage Stability: Material remains stable for at least 12 months under recommended conditions
Exposure Limits: No established occupational exposure limits, recommend keeping exposures as low as possible
Engineering Controls: Use local exhaust ventilation, provide eyewash stations and safety showers near handling areas
Respiratory Protection: Use NIOSH-approved respirators if exposure limits are likely to be exceeded
Hand Protection: Wear chemical-resistant gloves, such as nitrile or neoprene
Eye Protection: Safety goggles with side shields, face shield for splash risk
Skin Protection: Impervious protective clothing, lab coats, aprons
Appearance: Clear, colorless to pale yellow liquid
Odor: Mild, typical of organosilane compounds
Odor Threshold: No data available
pH: Not applicable (reacts with water)
Melting Point/Freezing Point: -60 °C
Boiling Point: 290 °C
Flash Point: 138 °C (closed cup)
Evaporation Rate: Slower than water
Flammability: Low, vapors may be combustible
Vapor Pressure: 0.1 mmHg at 20 °C
Vapor Density: Heavier than air
Relative Density: 1.07–1.10 g/cm³ at 25 °C
Solubility: Reacts slowly with water, soluble in most organic solvents
Partition Coefficient (n-octanol/water): Not determined
Auto-ignition Temperature: > 250 °C
Decomposition Temperature: Not specified
Viscosity: About 10–15 mPa·s at 25 °C
Chemical Stability: Stable under normal storage and use conditions, hydrolyzes in the presence of water
Reactivity: Can react with strong oxidizing agents, acids, and bases, moisture-sensitive
Hazardous Reactions: May undergo exothermic polymerization if mixed with strong acids or bases
Decomposition Products: Carbon oxides, siloxanes, silica fumes, low molecular weight organic compounds
Corrosivity: Not corrosive to metals
Acute Toxicity: LD50 (oral, rat) roughly 7 g/kg,
Inhalation: May cause respiratory tract irritation, coughing, shortness of breath
Skin Contact: Causes irritation, possible sensitization
Eye Contact: Causes significant irritation, redness, blurred vision
Chronic Effects: Prolonged exposure raises risk for mutagenicity, not classified as carcinogenic to humans by main agencies
Other Effects: No teratogenic or reproductive toxicity in animal studies
Aquatic Toxicity: Low acute toxicity to aquatic life (LC50 fish > 100 mg/L)
Persistence and Degradability: Slowly hydrolyzes in water to silanols and ethanol, main byproducts degrade with time
Bioaccumulation: Not expected due to rapid hydrolysis
Mobility in Soil: Mobile before hydrolysis, quickly binds after reaction with moisture
Other Adverse Effects: Avoid releases to the environment, not classified as a marine pollutant
Waste Treatment Methods: Dispose of waste through licensed chemical disposal contractors
Contaminated Packaging: Empty containers completely, reuse or recycle where possible, puncture and dispose of according to local regulations
Special Precautions: Do not mix with municipal waste or pour into drains, treat as hazardous waste under many local codes
Incineration: Suitable for high temperature incineration by professionals
UN Number: Not regulated for transport under ADR/RID, IMDG, ICAO/IATA
Proper Shipping Name: Organosilane compound, not classified as dangerous goods
Packing Group: None assigned
Labeling Requirements: Standard chemical labeling, no specific transport pictograms
Environmental Hazards: Not considered hazardous during transport, advise against transport with oxidizing agents or under damp conditions
TSCA Listing: Listed
REACH Registration: Registered, subject to specific conditions in the EU
OSHA Hazard Communication: Considered hazardous under OSHA criteria
EINECS/ELINCS Number: 220-941-2
SARA Title III: Not listed under Section 313
California Proposition 65: Not listed
International Inventories: Listed in main chemical inventories (Canada, Australia, Japan, China, Korea)
Workplace Labeling: Comply with all workplace hazard communication standards, display hazard, precaution, and safety instructions
