Chemical Name: 3-Methacryloyloxypropyltrimethoxysilane
Synonyms: γ-Methacryloxypropyltrimethoxysilane, Silane coupling agent
CAS Number: 2530-85-0
Recommended Use: Additive in adhesives, sealants, resins, plastics, surface modifiers
Manufacturer Contact: Emergency phone number, email address, and physical office location listed on container or supplier website
GHS Classification: Skin irritation, Serious eye irritation, Respiratory irritation
Signal Word: Warning
Hazard Statements: Causes serious eye irritation, May cause skin irritation, Harmful if inhaled
Pictograms: Exclamation mark symbol
Precautionary Statements: Avoid breathing vapors, Use protective gloves and safety goggles, Wash hands thoroughly after handling, Use in well-ventilated area
Chemical Identity: 3-Methacryloyloxypropyltrimethoxysilane
CAS Number: 2530-85-0
Concentration: ≥98% pure
Impurities: Residual methanol (possible byproduct), trace siloxanes indicated on supplier certificate of analysis
Inhalation: Move person to fresh air, keep at rest, seek medical advice if symptoms persist
Skin Contact: Wash with plenty of soap and water, remove contaminated clothing, seek attention if irritation develops
Eye Contact: Rinse immediately with water for several minutes, remove contact lenses if present and easy to do, seek medical help
Ingestion: Rinse mouth, do not induce vomiting, seek medical attention if unwell
Suitable Extinguishing Media: Water spray, dry powder, carbon dioxide, alcohol-resistant foam
Unsuitable Media: Direct water jet may spread fire
Hazards: Vapors may form explosive mixture with air; thermal decomposition yields carbon oxides and silicon oxides
Protective Equipment: Wear self-contained breathing apparatus, fire-resistant suit, stay upwind
Special Procedures: Avoid inhalation of combustion products, evacuate area, contain run-off from fire control
Personal Precautions: Wear gloves, goggles, respirator if ventilation is poor
Environmental Precautions: Prevent further leakage, do not let material enter sewers or surface water
Clean-up Methods: Absorb with inert material such as sand, shovel into closed chemical waste container, ventilate spill area, wash residues with plenty of water
Reference to Other Sections: For safe handling and disposal, see related recommendations
Handling: Keep containers tightly closed, avoid contact with skin and eyes, use only with recommended protective equipment, avoid inhaling vapors
Storage: Store in original container, cool and dry place, keep away from heat or sparks, protect from moisture
Incompatible Materials: Strong acids, strong bases, oxidizing agents, water (hydrolysis may occur releasing methanol)
Safe Practices: Use only as directed, ensure proper labelling of all containers
Occupational Exposure Limits: No established limits for this compound; monitor for possible methanol vapors
Engineering Controls: Use fume hood or mechanical ventilation, eyewash station and emergency shower accessible in work area
Protective Equipment: Chemical-resistant gloves, safety goggles, lab coat, NIOSH-approved respirator if exposure limits for methanol are exceeded
Hygiene Measures: Do not eat, drink or smoke during use; wash hands and forearms after handling
Appearance: Colorless to yellowish transparent liquid
Odor: Characteristic, slightly acrid
Molecular Weight: 248.36 g/mol
Melting Point: Freezing point below -50°C
Boiling Point: 255°C at 760 mmHg
Flash Point: 108°C (closed cup)
Density: 1.045–1.060 g/cm³ at 25°C
Solubility: Hydrolyzes and forms insoluble products in water; miscible in most organic solvents
Vapor Pressure: About 0.5 mmHg at 20°C
pH: Not applicable (neutral in dry state)
Chemical Stability: Stable under recommended storage conditions
Reactivity: Reacts with moisture, acids, and bases
Hazardous Reactions: Contact with water or humid air releases methanol
Conditions to Avoid: Contact with water, extreme heat, direct sunlight
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, silicon oxides, methanol fumes
Acute Toxicity: LD50 (oral, rat): about 7,960 mg/kg
Inhalation: Irritating to respiratory tract; high exposures may cause central nervous system depression
Skin Contact: Repeated or prolonged exposure can cause irritation
Eye Contact: Can cause severe irritation, redness, watering
Sensitization: Rare reports of skin sensitization in some workers
Long-Term Effects: Prolonged exposure to methanol byproduct can affect organs including liver, kidney, nervous system
Mutagenicity/Carcinogenicity: No clear evidence according to available studies up to 2024; not listed as carcinogen by NTP, IARC, OSHA
Aquatic Toxicity: Low toxicity to fish and aquatic life; breakdown products may be dangerous to aquatic organisms
Persistence and Degradability: Undergoes hydrolysis in water; primary breakdown leads to methanol and insoluble siloxanes
Bioaccumulation: Low potential based on physicochemical data
Mobility in Soil: Rapid degradation limits migration; possible leaching of methanol into groundwater
Other Adverse Effects: No major impact at recommended use concentrations; avoid contamination of water systems
Waste Treatment: Incinerate at approved waste disposal facility; avoid landfilling hazardous liquid
Disposal Containers: Place contaminated absorbents or residues in sealed, labelled chemical waste drums
Special Precautions: Do not flush to sewer, do not release to the environment. Dilute and treat residuals under supervision of a licensed professional
Regulatory Considerations: Product and packaging classified as hazardous waste in most jurisdictions; consult local and national regulations for compliance
UN Number: 1993 (Flammable liquids, n.o.s.; includes methanol)
Proper Shipping Name: Flammable liquid, organic, n.o.s. (contains methanol)
Transport Hazard Class: Class 3 (Flammable liquid)
Packing Group: III
Environmental Hazards: Avoid release into environment during transit
Special Transport Precautions: Use tightly sealed containers, label and document according to ICAO/IATA, IMDG, ADR, DOT requirements
Labeling Requirements: GHS/OSHA HazCom-compliant labeling with hazard pictograms and text
Inventory Status: Listed on TSCA (USA), EINECS/ELINCS (EU), DSL (Canada), ENCS (Japan)
SARA Title III (Sections 311/312): Acute health hazard, fire hazard
California Proposition 65: Methanol byproduct is listed due to reproductive toxicity
Right to Know: States including New Jersey, Pennsylvania, Massachusetts require workplace notification
Chemical Safety Assessment: Required by REACH in the European Union; consult SDS for updates as regulations evolve
