Product Name: 3-Ureidopropyltrimethoxysilane
Chemical Formula: C7H18N2O4Si
Synonyms: Gamma-Ureidopropyltrimethoxysilane
CAS Number: 23843-64-3
Recommended Use: Coupling agent for adhesives, sealants, coatings, and surface treatments
Manufacturer Information: Supplier details provided on request
Emergency Contact: Chemtrec +1-800-424-9300 (USA), available 24 hours
Classification: Eye Irritant Category 2A, Skin Sensitizer Category 1, Acute Toxicity Category 4 (oral)
Signal Word: Warning
Pictograms: Exclamation Mark
Hazard Statements: Causes serious eye irritation, may cause an allergic skin reaction, harmful if swallowed
Precautionary Statements: Avoid contact with skin and eyes, wear protective gloves and eyewear, wash thoroughly after handling
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Potential Symptoms: Itching, redness, eye watering, respiratory discomfort
Chemical Name: 3-Ureidopropyltrimethoxysilane
CAS Number: 23843-64-3
Concentration: 95% or greater
Other Components: Methanol (possible as hydrolysis byproduct, trace amounts), impurities < 1%
Inhalation: Remove victim to fresh air, provide oxygen if breathing is difficult, seek medical attention if irritation persists
Skin Contact: Remove contaminated clothing, wash affected area with soap and water, do not reuse contaminated clothing before washing, medical help if irritation continues
Eye Contact: Hold eyelids open, rinse gently under running water for at least 15 minutes, move eyes in all directions, remove contacts if present and easy, contact physician
Ingestion: Do not induce vomiting, rinse mouth with water, never give anything by mouth to someone unconscious, call a poison center or doctor immediately
Note for Physician: Treat symptomatically, support respiratory and cardiovascular functions as needed
Suitable Extinguishing Media: Dry chemical, CO2, foam, water spray (for large fires)
Unsuitable Media: High pressure water jets may spread the product
Hazards During Fire: May release toxic fumes like carbon monoxide, carbon dioxide, nitrogen oxides, and silicon oxides
Protective Equipment: Full protective gear, self-contained breathing apparatus
Special Precautions: Evacuate the area, fight fire from safe distance, use water spray to cool exposed containers, contain runoff to prevent environmental contamination
Personal Precautions: Avoid inhalation and direct contact, wear chemical-resistant gloves, splash goggles, and protective clothing
Spill Clean-up: Absorb with inert material (sand, earth), avoid using sawdust or combustible absorbents, place in proper waste containers
Environmental Precautions: Do not allow product to enter drains, waterways, or soil
Methods for Containment: Prevent further leakage or spillage if safe to do so, ventilate area
Disposal: Comply with local, regional, and national regulations for disposal of chemical wastes
Safe Handling: Use in well-ventilated areas, avoid breathing vapors or mists, avoid skin and eye contact, keep away from food and beverages, wash thoroughly after use
Storage Conditions: Store in tightly closed original container, cool, dry, well-ventilated place, protect from freezing and direct sunlight
Incompatibilities: Avoid contact with water, strong oxidizing agents, acids, bases
Special Requirements: Use secondary containment for bulk storage, segregate from incompatible substances
Engineering Controls: Use local exhaust ventilation, safety showers, and eyewash stations in immediate vicinity
Exposure Limits: No established occupational exposure limit (OEL) for this specific compound; use methanol limits as reference if hydrolysis occurs (ACGIH TLV: 200 ppm TWA)
Personal Protective Equipment: Chemically-resistant gloves (nitrile or neoprene), safety goggles or face shield, lab coat/chemical apron, respiratory protection if ventilation insufficient
Hygiene Measures: Avoid transferring contaminated materials to other areas, wash hands and any exposed skin before breaks and at end of work
Environmental Controls: Prevent release to the environment by using proper containment and disposal methods
Appearance: Clear to pale yellow liquid
Odor: Slight amine-like
Odor Threshold: Not available
pH: Approximately 7 (as supplied)
Melting Point / Freezing Point: Not determined
Boiling Point: Approximately 230°C (446°F) at atmospheric pressure
Flash Point: >100°C (212°F) closed cup
Evaporation Rate: Not established
Flammability: Not highly flammable, vapors may form explosive mixtures at high temperatures
Vapor Pressure: Very low at 20°C
Vapor Density: Heavier than air
Relative Density: Approximately 1.12 g/cm³ at 20°C
Solubility: Reacts slowly with water, soluble in many organic solvents
Partition Coefficient (n-octanol/water): Not determined
Auto-ignition Temperature: Not determined
Decomposition Temperature: Not available
Viscosity: Not available
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: Reacts slowly with moisture, forming methanol
Hazardous Reactions: May produce methanol and silanol by hydrolysis, risk of hazardous reactions increases in presence of strong acids or bases
Conditions to Avoid: Avoid moisture, prolonged exposure to heat, direct sunlight
Incompatible Materials: Avoid strong oxidizers, strong bases and acids, water, aluminum, and zinc
Hazardous Decomposition Products: Methanol, formaldehyde, oxides of nitrogen, silicon dioxide, and carbon monoxide/carbon dioxide
Likely Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Harmful if swallowed (LD50 oral rat: >500 mg/kg)
Skin Corrosion/Irritation: May cause moderate inflammation with repeated or prolonged contact
Serious Eye Damage/Irritation: Causes eye irritation
Respiratory Sensitization: Not classified, but inhalation may cause local discomfort
Skin Sensitization: May cause allergic skin reaction
Carcinogenicity: No available evidence for carcinogenic potential
Germ Cell Mutagenicity: Data not sufficient
Reproductive Toxicity: Data not sufficient
Specific Target Organ Toxicity (Single Exposure): May cause drowsiness or dizziness if significant methanol is liberated
Aspiration Hazard: Not expected under normal use
Aquatic Toxicity: Toxic to aquatic organisms with long lasting effects (algae EC50: 10–100 mg/L, Daphnia EC50: 10–100 mg/L, theoretical based on similar compounds)
Persistence and Degradability: Product hydrolyzes slowly in water forming silanols and methanol, which degrade further
Bioaccumulation Potential: Not expected to bioaccumulate (Log Kow estimated < 3)
Soil Mobility: Moderate mobility, partially adsorbs to soil particles
Other Adverse Effects: No known significant effects or hazards not discussed in this document
Waste Disposal: Collect and dispose of in accordance with federal, state, and local environmental control regulations, do not release untreated product to sewers or waterways
Container Disposal: Triple rinse, puncture, and send to approved industrial waste facility, avoid reuse of emptied containers
Special Instructions: Do not incinerate in closed containers, handle waste only with properly trained personnel, label all disposal containers clearly
UN Number: Not classified as hazardous for transport by most regulatory agencies
Proper Shipping Name: Not regulated
Hazard Class: Not applicable
Packing Group: Not applicable
Marine Pollutant: Not listed, avoid bulk releases to water due to aquatic toxicity
Special Precautions: Ensure containers remain tightly sealed and secure during transit, avoid extreme temperatures
Transport Labels: None required by most ground, air, or sea transport regulations
OSHA (USA): Not specifically listed as hazardous, but general chemical safety applies
TSCA Inventory: Listed
REACH (Europe): Registered or pre-registered substance
WHMIS (Canada): D2B (Toxic material causing other toxic effects, irritation, sensitization)
SARA Title III: No reportable quantities under Sections 302, 304, 313
California Proposition 65: Methanol, a potential hydrolysis byproduct, is listed for reproductive toxicity
RoHS / ELV / GHS: Product meets current guidelines for chemical content and labelling
Chemical Safety Assessment: Carried out for this substance
