Scientists chasing better ways to link inorganic surfaces with organic chemistry started playing with silane coupling agents in the middle of the twentieth century. Out of these efforts came Bis[3-(Triethoxysilyl)Propyl]Amine, sometimes called BTESPA. This compound got a boost from both the electronics boom and the push for more advanced coatings and adhesives. Laboratories that used to stick to simpler silanes began to look for molecules that could bring two surfaces together more effectively. They found that adding an amine group along with triethoxysilane groups improved adhesion in tough environments. Industry and academic labs hooked onto BTESPA for its versatility. As folks at Dow Corning, Momentive, and Evonik kept pushing the boundaries, they contributed data and real-world use cases that made this aminosilane a staple in surface science circles.
Bis[3-(Triethoxysilyl)Propyl]Amine shows up as a pale yellow liquid that people working with advanced materials get to know quickly. Its formula—C18H43NO6Si2—ends in the telltale “-amine” adding new bonding possibilities on top of the silane base. Suppliers and formulators grab it for its dual-reactive capability. It can stick to glass, metals, and ceramics on one end while linking with organic resins like epoxy, urethane, or acrylic on the other. Most applications don’t need complicated equipment or specialized storage. That trait opened the door for adoption in both high-tech and more practical arenas, from circuit boards to painted steel beams.
BTESPA weighs in at about 437 grams per mole and its boiling point lands above 300°C—well past the degradation point for most resins. Viscosity stays manageable and pouring remains easy at room temperature, which prevents a lot of headaches during mixing. Hydrophobic interactions from the ethoxy groups give this silane good resistance to moisture when cured, but the neat liquid does take up some water if left open to air for too long. Its amine content drives reactivity with epoxies and isocyanates, letting composite manufacturers fine-tune interfaces right down to the molecular level. The signature odor can clue in experienced chemists that they have a functionalized silane on their hands.
Quality standards for Bis[3-(Triethoxysilyl)Propyl]Amine demand transparency and numbers that end-users can trust. Density hovers near 0.97 to 1.00 g/cm³ at room temperature. The amine content often gets checked by titration and should meet the supplier’s certificate of analysis. Labels include the CAS number 1760-24-3, and documentation often highlights impurity levels of chlorides or residual alcohols. Drums and kegs carry warnings for flammability and skin corrosion. From experience in the lab, a clear, full label prevents mix-ups, especially when similar-looking silane batches get delivered side by side.
Manufacturers make BTESPA by reacting 3-chloropropyltriethoxysilane with ammonia or organic amines in the presence of a base. This pathway lets them dial in the ratio and purity, and experienced chemists know to keep moisture at bay during synthesis. You can spot smaller producers running batch reactors, while global suppliers switch to continuous operation for better scale and consistency. Each batch gets checked for leftover reactants or byproducts, especially water, which can foul up polymerization later. The synthetic recipe, honed over decades, allows for tweaks that improve shelf life and reactivity. This attention to detail reflects tough expectations from buyers in coatings, adhesives, and aerospace fields.
BTESPA shines because it bridges two worlds: the silane ends hydrolyze and tie down to surfaces like silica, alumina, and glass, while the amine group grabs onto reactive partners like epoxies, polyurethanes, and carboxylic acids. Years in composite workshops teach the value of this dual-action: parts stick together longer, water doesn’t seep in, and aging slows down. Chemists know they can tweak BTESPA, swapping in different amines or silane backbones for specialized needs. Crosslinking with polyisocyanates, or grafting onto nanoparticle surfaces, underscores just how adaptive this molecule has become in modern labs.
Alongside its systematic name, Bis[3-(Triethoxysilyl)Propyl]Amine goes by shorter tags such as BTESPA or simply “aminosilane.” Product codes like A1130 (from Momentive) or Dynasylan 1124 (Evonik) pop up in catalogs from major suppliers. Some manufacturers list it under “bis-aminopropyltriethoxysilane” or call out the dual silane link explicitly. Even with this naming overlap, someone with a bit of industry know-how can trace most synonyms back to the same functional family. Naming clarity matters so customers don’t get stuck with the wrong compound in a critical batch.
Anyone working with BTESPA learns quickly to respect its reactivity. Contact with moisture before use triggers premature hydrolysis, which can gum up labware or cause skipping during surface treatments. Gloves, goggles, and fume extraction are standard, as vapor and liquid can both irritate skin or airways. In my time on the shop floor, even seasoned technicians double-check storage in the original, unopened drum. OSHA classifies it as hazardous for both inhalation and skin exposure. Training focuses not only on spills and splashes, but also on keeping material away from food prep or poorly ventilated corners. Regular checks on storage temperature and container seals keep both people and products safe.
BTESPA gets called into action in a long list of industries. Fiber-reinforced plastics, advanced coatings, and circuit board fabrication all use this aminosilane to improve durability and bonding. In automotive plants, it gets brushed onto glass and metal before painting or gluing. Construction crews rely on it for anti-corrosion treatments on exposed steel frameworks—rain or shine—because it stands up to both weather and chemical attack. Lab techs prepping a batch of silica nanoparticles for drug delivery uses lean on BTESPA for better stability and bio-compatibility. Its role as a primer, adhesion promoter, and crosslinker reaches throughout electronics, medical devices, and even oil-field chemistry.
Lab teams keep finding new tricks for BTESPA. In polymer research, it plays a key role in forming abrasion-resistant films or hydrophobic coatings. Nanotechnology specialists use it to anchor gold or silver particles onto glass, creating surfaces for diagnostics or catalysis. BTESPA-modified resins have shown improved resistance to both salt water and solvents—a huge plus for protective paints on ships or offshore rigs. Efforts to graft biologically active molecules onto medical-grade glass rely on aminosilanes to get the chemistry right. Patent filings from 2020 onward show a steady drumbeat of inventors extending BTESPA’s reach, from hybrid materials to new classes of adhesive films and self-healing composites.
Safety teams and toxicologists recognize that BTESPA, like most organosilanes, needs respectful handling. Animal studies on similar silanes suggest low acute toxicity by skin contact or inhalation, though eye contact can cause lasting irritation and repeated exposure sometimes sensitizes staff. Chronic effects remain under investigation, but regulators haven’t flagged this compound for severe long-term risks at normal exposure levels in well-controlled workplaces. Researchers keep testing possible byproducts and impurities as manufacturing scales up. Real-world experience from years of bulk use backs up the official safety sheets: spill kits, PPE, and ventilation go far to prevent harm.
Demand for more durable, lightweight, and eco-friendly materials keeps pushing chemists to look for reliable coupling agents. BTESPA’s unique mix of silane and amine functionality puts it front and center as industries move toward smarter composites and stronger, longer-lasting adhesives. As energy infrastructure upgrades, and electronics shrink to even tighter tolerances, need for robust surface coupling is going nowhere but up. In environmental circles, researchers look for greener silanes with bio-based or even recyclable linkers—an area ripe for BTESPA-inspired innovation. Whether it’s for medical diagnostic chips, corrosion proofing, or new flexible electronics, the foundation laid by this aminosilane powers the next generation of materials science.
Walk into any lab that deals with surface chemistry or advanced materials, and sooner or later, a bottle labeled “Bis[3-(Triethoxysilyl)Propyl]Amine” shows up. Chemists might call it a silane coupling agent. Most people haven’t heard of it, but it plays a pretty important part in making science work in daily life. Sure, the name feels a mile long, but its main trick comes down to connecting things that don’t naturally like to stick together — stuff like glass and plastic, or ceramics and resins.
Years ago in a research internship, I came across this compound while digging into why certain glues hold up better in harsh weather. Turns out, it played a role in one of the “secret sauces” behind adhesion. Picture a composite wind turbine blade, layered with fiberglass and resin. Without a solid bond, those layers peel apart, especially after sun, rain, and years of vibration take their toll. In steps Bis[3-(Triethoxysilyl)Propyl]Amine: the molecule has a foot in the world of glass (the triethoxysilyl part) and another in the world of organic polymers (the amine part). It welds those two different worlds together on a microscopic level. Not just in wind turbines, but in bridges, cars, boats, and even sports equipment.
Manufacturers rely on it not just for strength but for weather resistance too. Silane coupling agents like this one help coatings last longer, fight off corrosion on metal surfaces, and boost durability of plastics. In electronics, engineers use it in circuit boards to reinforce adhesion between components and base materials. A lot of the final device testing centers on reliability, and this molecule helps meet those standards.
No story about a chemical should leave out the health and safety part. Workers handle Bis[3-(Triethoxysilyl)Propyl]Amine in ventilated rooms, with gloves and goggles — not because it’s instantly deadly, but because skin and eye irritation can creep up with sloppy handling. Fact: safety data sheets flag the importance of protective gear, and the European Chemicals Agency lists it as a chemical needing respect but not panic.
Environmental concerns follow the same general playbook as other organosilanes. Waste management protocols keep it out of the water supply, and guidance for storing and recycling containers runs tight. Green chemistry pushes aim to trim down waste and swap out problematic solvents where the compound gets used. Few things disappear from the industrial world overnight, though, so the best approach looks like tighter training for workers and ongoing surveillance for leaks or misuse.
From personal experience, small changes in how companies use Bis[3-(Triethoxysilyl)Propyl]Amine can make a big difference. Labs often test lower concentrations or explore alternatives with fewer side effects. Transparency matters as well — people deserve to know what’s in the stuff touching their lives, whether it’s in paint on their walls or coatings on their phone screens. Scientists keep working on greener, safer coupling agents, but for now, this molecule stays present in industries where strong and lasting bonds save money, lives, and resources. That’s the kind of unsung role chemistry plays every day.
A lot of specialty chemicals ask for extra attention, but Bis[3-(Triethoxysilyl)Propyl]Amine isn’t just another bottle on a shelf. Storing it the right way isn’t about ticking rules off a list—it’s about safety, stable performance, and money saved from avoiding spoiled stock. I’ve walked into enough labs and factories to know some products get forgotten or left by the radiator. This one cannot join the pile.
What’s inside the bottle, after all, wants to face away from water and heat. The triethoxysilyl groups act like sponges for moisture, and water triggers those unwanted chemical changes. Pop the cap in a high-humidity room and you’ll see cloudy liquid or white goop before long. Risks like this go beyond a ruined batch: broken experiments, strange surface finishes, or wasted time usually follow.
Real experience has taught me that an air-conditioned storeroom or a steady 20°C lab cupboard works much better than a drafty shelf. Direct sunlight cooks up trouble. Fluctuating temperatures or muggy storage closets can generate mystery substances and even pressure in the container. Several researchers I know learned this the hard way when they stored their silanes near an outside wall—winter condensation led to surprise leaks and dark splotches on the bench.
A tightly sealed original container gives you extra protection. Even after many years, that inner seal has kept the air out for me—and chemicals inside have stayed clear. Don’t bother transferring to fancy glass decanters or repurposed jars; stick to the original packaging, especially if it’s aluminum-lined or lined with a moisture barrier.
Labs that get this storage step wrong end up with flammable fumes from hydrolysis or off-gassing. Breathing problems and even fires trace back to badly stored small molecules. Workers in a friend’s lab found sticky residue under old bottles, a sign that streamlining or penny-pinching storage habits can suddenly cost much more. So always check that shelf label: away from acids, alkalis, and oxidizers. Forgetting this small detail sent one company I worked with into a full hazardous waste cleanup, costing days and thousands in cleanup fees.
A dedicated lockable cabinet, out of sunlight and away from busy aisles, makes sense. Install inexpensive digital thermometers and humidity sensors; if you hit more than 60% humidity or 25°C, move stock to a better spot. Rotate containers so oldest gets used first, and mark every open container with the date. Replacing the desiccant or adding one keeps moisture away. And don’t ignore training—every new worker should know what goes where and why, not just because the chemical label says so, but because of real-life failures others have seen.
From years of handling organosilanes, there’s one lesson to share: don’t trust luck to keep your product intact. Plan your storage, and you’ll keep both your staff and results far away from trouble.
Bis[3-(Triethoxysilyl)propyl]amine carries the formula C18H43NO6Si2. Its structure shows two identical triethoxysilylpropyl groups bonded to a central nitrogen atom, resulting in a molecule that packs both organic flexibility and silicon-based reactivity. The calculated molecular weight lands at 437.72 g/mol, a figure that gives chemists and engineers a reference point for precise formulations.
There’s something fascinating about silanes like this one. You can’t walk into a research lab or a manufacturer focusing on surface coatings or adhesives without running into organosilanes. I remember handling triethoxysilyl-based substances as an undergraduate in polymer labs; every step relied on understanding how these compounds built bridges between organic chains and inorganic surfaces. Bis[3-(Triethoxysilyl)propyl]amine finds its use as a coupling agent and adhesion promoter because of this dual nature. The three ethoxy groups attached to each silicon atom react easily with glass, ceramics, and metals at relatively mild temperatures, offering a durable link to polymer matrices.
Over time, I’ve seen composite materials that once struggled with peeling or premature failure get a second chance. A little silane goes a long way to form chemical bonds at the microscale, turning surfaces from weak points into strong, interconnected networks.
Chemical workers face exposure risks every day. Silane-based amines like this carry their own set of safety requirements. The ethoxy groups can hydrolyze and release ethanol, which is flammable and potentially irritating if concentrations rise. Amine functionality raises additional questions, prompting use of gloves, goggles, and ventilation. From personal experience, even low concentrations become a headache in poorly managed spaces. Keeping MSDS sheets at hand, running fume hoods, and using tight-sealing containers reduces these routine risks.
Disposal also deserves a closer look. Waste streams holding silicon-based organics can affect wastewater treatment plants, since some degrade slowly or break into persistent residues. Research has taken important steps to study the long-term impact of silanes in environmental systems. I’ve spoken with researchers exploring advanced oxidation processes and biological systems to safely manage these materials after use. This part of the story often gets overlooked, but it shapes guidelines on worker safety and sustainable disposal.
Problems aren’t solved solely by new molecules; they take reliable data, real-world testing, and a willingness to learn from error. Bis[3-(Triethoxysilyl)propyl]amine shows up in applications from electronics to construction, creating hybrid surfaces with added value. Yet quality control sometimes lags behind. Using pure starting materials, monitoring hydrolysis, and controlling reaction conditions all shape whether the end product performs a year from now.
If technical teams invest in better staff training and rigorous analytical methods—NMR, FTIR, chromatography—the consistency improves. Relying on government research and feedback from early adopters shapes safe and effective processes. Regular updates to environmental and handling protocols reflect new findings. That’s how genuine progress emerges in chemical manufacturing, from the small habits in the lab to company-wide safety initiatives.
If you work in materials science or industrial manufacturing, you’ve probably bumped into bis[3-(triethoxysilyl)propyl]amine—sometimes just called "amino silane." It’s found in adhesives, coatings, and even electronics. On paper, it sounds harmless: folks use it as a binding agent, it helps surfaces stick, and it won’t grab headlines like some infamous chemicals. Yet, the real question is whether it's dangerous or something you need to handle with extra care.
Many chemical substances have long, intimidating names and unclear reputations. With bis[3-(triethoxysilyl)propyl]amine, lab data actually brings some clarity. The European Chemicals Agency (ECHA) labels it as causing irritation to skin and eyes. In my lab days, any chemical that irritates eye tissue or skin earns respect—even if it doesn't seem deadly or acutely toxic. Workers sometimes dismiss risks until burns or rashes hit.
Inhaling or spilling the liquid can set off coughing, sneezing, and itchiness. Sometimes, reactions feel mild and fade quickly if you wash up fast. Long-term effects remain murkier. Animal studies haven’t produced evidence of severe hazard—no cancers, no DNA damage, not even allergic reactions. Humans can still have outlier reactions. Anyone who’s had a chemical splash knows that those rare, unlucky moments hurt the most.
Companies shipping this compound include hazard symbols: protective gloves, goggles, and a fume hood are all recommended. These aren’t suggestions just to check boxes. The chemical breaks down if water or humidity gets involved, releasing byproducts like ethanol. Multiple small exposures over years carry more weight than a single splash. I’ve seen workers get overconfident, skip gloves, then regret it after a burning sensation takes over.
Environmental risk is worth asking about, too. Studies hint that most aminosilanes break down in soil and water, but breakdown doesn’t happen overnight. Silanes attach to dust and linger on surfaces if spills aren’t cleaned up right away. Past experience taught me a lab bench will stay sticky and odd-smelling for days if you treat “routine chemicals” casually. Companies that train staff, keep safety data sheets close, and stick to chemical safety routines avoid long-term issues, both with regulators and the people in the lab.
Some folks feel tempted to dismiss lower-profile chemicals, thinking that only things with skull-and-crossbones icons really matter. My take: you don’t want to cut corners, since exposure can add up quietly. Checking the Globally Harmonized System (GHS) helps—a compound classified for skin and eye damage deserves real respect, even if it’s not deadly. Simple fixes—ventilation, gloves, good labeling—stop problems before they start.
Using less hazardous alternatives, if they're available, always appeals to me, but sometimes you’re stuck with what works best for your process. That’s where transparency about risks, honest communication, and access to info come in. Bis[3-(triethoxysilyl)propyl]amine isn't some mystery threat, but it’s not a free pass either. Respect the label and you’ll keep your skin, lungs, and reputation intact.
Bis[3-(Triethoxysilyl)Propyl]Amine doesn’t show up on grocery store shelves — it works behind the scenes in advanced coatings or adhesives. The chemical bonds it forms help products last longer. But if you’ve ever looked up its safety data, you’ll spot some warnings right away. Direct skin or eye contact can burn. Inhaling fumes or swallowing the substance can trigger headaches or worse. So, handling this stuff safely isn’t just about ticking boxes. Sticking to tried-and-true steps protects workers, nearby communities, and the environment.
Folks working with any silane should reach for gloves, goggles, and a sturdy lab coat before they even pop the cap off a container. Respiratory masks take away the guesswork when vapor risk gets mentioned in safety sheets. Laboratories and chemical plants know this drill. I’ve seen training sessions turn skeptical newcomers into the loudest voices for double-checking gear. A splash or mist goes further than people expect, so real attention to detail matters.
Companies often post handling procedures on bright posters next to workstations. Eyes aren’t supposed to gloss over routine reminders, and supervisors follow up to keep routines sharp. Well-lit, ventilated rooms help keep spills contained. No one wants to deal with what happens if this compound hits moisture or the wrong substance and starts reacting. Fast access to eyewash stations or safety showers isn’t overkill; it’s a baseline.
This chemical stays fresher and safer in snug, labeled containers. Metal or sturdy plastic drums, never glass jars. Placement counts, too — not close to acids or bases, not in direct sunlight, not near something that sparks. I once saw a warehouse manager haul out an entire shelf of products after realizing incompatible chemicals shared an aisle. Paper logs and regular stock checks stop errors before they start. Peace of mind has a shelf life, just like the product itself.
Pouring leftovers down the drain isn’t an option. Municipal water treatment plants aren’t built to handle this kind of waste. I’ve spoken with waste contractors who’ve seen nasty surprises turn up in private septic tanks and rivers downstream of old industrial sites. The right move is clear: collect all unused or contaminated Bis[3-(Triethoxysilyl)Propyl]Amine in sturdy, sealed containers. Mark labels to help everyone know what’s inside and when it showed up.
Licensed hazardous waste handlers know the ropes here. Incineration by professionals — in a facility designed to cut down toxic byproducts — keeps pollutants from ever reaching fields or streams. Records matter just as much as the actual disposal. Regulators ask for paperwork tracing every step from warehouse shelf to treatment furnace. Auditors will flag gaps. Cutting corners just leads to bigger problems later.
Companies have started asking deeper questions about what happens to chemicals after they’re sold or used. Some now run staff through realistic drills built on real accidents, not just theoretical risks. Newer technologies help monitor air quality in real time. Transparent reporting in compliance logs helps authorities spot companies doing the right thing—and shine a light on those who dodge responsibility.
No one expects a facility to reach perfection every day. But a culture of care beats a binder full of rules any day. Sharing real stories, not just data, reminds workers and management what’s at stake: health, safety, and a clean environment for everyone.
![Bis[3-(Triethoxysilyl)Propyl]Amine](/static/26ffdaf2-b05a-4718-b9a8-e71fecc06434/images/2d/bis-3-triethoxysilyl-propyl-amine.png)
![Bis[3-(Triethoxysilyl)Propyl]Amine](/static/26ffdaf2-b05a-4718-b9a8-e71fecc06434/images/3d/bis-3-triethoxysilyl-propyl-amine.gif)
| Names | |
| Preferred IUPAC name | Bis[3-(triethoxysilyl)propyl]amine |
| Other names |
Amino-bis(trimethoxysilylpropyl) Bis(3-triethoxysilylpropyl)amine N-[3-(Triethoxysilyl)propyl]-3-(triethoxysilyl)propan-1-amine Bis(3-(triethoxysilyl)propyl)amine |
| Pronunciation | /ˈbɪs θri traɪˌɛθɒksiˌsɪlaɪl ˈproʊpɪl əˈmiːn/ |
| Identifiers | |
| CAS Number | 1760-24-3 |
| Beilstein Reference | 5444440 |
| ChEBI | CHEBI:82605 |
| ChEMBL | CHEMBL3641705 |
| ChemSpider | 2223476 |
| DrugBank | DB22075 |
| ECHA InfoCard | ECHA InfoCard: 100.090.276 |
| EC Number | 245-617-4 |
| Gmelin Reference | 1264363 |
| KEGG | C14293 |
| MeSH | D016687 |
| PubChem CID | 102870 |
| RTECS number | TZ4300000 |
| UNII | H0K8M16NQX |
| UN number | UN3334 |
| CompTox Dashboard (EPA) | DTXSID20923956 |
| Properties | |
| Chemical formula | C18H43NO6Si2 |
| Molar mass | 463.75 g/mol |
| Appearance | Colorless to yellowish liquid |
| Odor | Amine-like |
| Density | 0.98 g/mL at 25 °C(lit.) |
| Solubility in water | Slightly soluble in water |
| log P | 0.1 |
| Vapor pressure | <0.01 hPa (20 °C) |
| Acidity (pKa) | Acidity (pKa): 8.2 |
| Basicity (pKb) | 6.65 |
| Magnetic susceptibility (χ) | -70.0E-6 cm³/mol |
| Refractive index (nD) | 1.427 |
| Viscosity | 2.5 cP (25 °C) |
| Dipole moment | 1.35 D |
| Pharmacology | |
| ATC code | V03AC04 |
| Hazards | |
| GHS labelling | GHS07, GHS05 |
| Pictograms | GHS07,GHS05 |
| Signal word | Warning |
| Hazard statements | H315, H319 |
| Precautionary statements | P261, P264, P271, P273, P280, P302+P352, P305+P351+P338, P308+P313, P312, P321, P332+P313, P337+P313, P362+P364, P501 |
| NFPA 704 (fire diamond) | 1-1-0 |
| Flash point | 80 °C |
| Lethal dose or concentration | LD50 Oral - Rat - > 2,000 mg/kg |
| LD50 (median dose) | LD50 (median dose): Oral rat LD50 > 2000 mg/kg |
| NIOSH | NT0800000 |
| PEL (Permissible) | 50 ppm |
| REL (Recommended) | 50 mg/m3 |
| Related compounds | |
| Related compounds |
3-Aminopropyltriethoxysilane Bis[3-(Trimethoxysilyl)Propyl]Amine N-Phenylaminopropyltrimethoxysilane Bis[3-(Triethoxysilyl)Propyl]Ether 3-Glycidoxypropyltriethoxysilane |
