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Material Safety Data Sheet for Bis[3-(Trimethoxysilyl)Propyl]Amine

Identification

Product Name: Bis[3-(Trimethoxysilyl)Propyl]Amine
Synonyms: N-[3-(Trimethoxysilyl)propyl]-3-aminopropyltrimethoxysilane
Molecular Formula: C18H45NO6Si2
Molecular Weight: 443.74 g/mol
Recommended Use: Silane coupling agent, surface modifier
Manufacturer: Company name and address supplied by provider
Emergency Telephone: Provided by manufacturer or supplier
CAS Number: 82985-35-1

Hazard Identification

Classification: Skin irritation (Category 2), Eye irritation (Category 2A), Specific target organ toxicity – single exposure (Category 3), Flammable liquids (Category 3)
GHS Label Elements: Pictograms: Exclamation mark, flame
Signal Word: Warning
Hazard Statements: Causes skin irritation; Causes serious eye irritation; May cause respiratory irritation; Flammable liquid and vapor
Precautionary Statements: Avoid breathing vapors; Wear protective gloves, eye protection; Keep away from heat, sparks, open flames; Use explosion-proof equipment; Ensure adequate ventilation

Composition / Information on Ingredients

Chemical Name: Bis[3-(Trimethoxysilyl)Propyl]Amine
CAS Number: 82985-35-1
Concentration: ≥ 95%
Impurities: Methanol may be released during hydrolysis; Trace siloxanes possible

First Aid Measures

Inhalation: Move to fresh air, support breathing, get medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, wash skin with soap and water for several minutes, seek medical advice if irritation develops
Eye Contact: Rinse eyes cautiously with water for several minutes, remove contact lenses if present, continue rinsing, seek medical help if eye irritation persists
Ingestion: Rinse mouth, never induce vomiting, seek immediate medical assistance, do not give anything by mouth to an unconscious person
Most Important Symptoms: Cough, shortness of breath, skin redness, eye watering, itching

Fire-Fighting Measures

Suitable Extinguishing Media: Alcohol-resistant foam, dry chemical powder, carbon dioxide, water spray (cooling only)
Specific Hazards: Vapors may travel to source of ignition, forms explosive mixtures with air, thermal decomposition releases formaldehyde, methanol, and toxic fumes
Special Protective Equipment: Full protective gear, self-contained breathing apparatus
Firefighting Instructions: Isolate area, prevent entry, cool containers exposed to flames, use water spray for cooling, avoid inhaling combustion products

Accidental Release Measures

Personal Precautions: Evacuate unnecessary personnel, ensure good ventilation, remove all ignition sources, avoid contact with skin and eyes
Spill Cleanup: Absorb with inert material (sand, earth), collect in appropriate closed containers, do not flush to sewer
Environmental Precautions: Prevent further leakage or spillage, keep out of water sources and sewers, report releases as applicable by law
Protection for Responders: Chemical-resistant gloves, goggles, protective clothing, avoid breathing vapors

Handling and Storage

Handling: Use only in well-ventilated areas, ground and bond containers, wear appropriate PPE, avoid inhalation of vapor or mist, avoid contact with eyes and skin, keep container tightly closed
Storage Conditions: Store in cool, dry place, away from sources of ignition and incompatible materials (acids, oxidizers, moisture), keep container tightly sealed, protect from moisture, store between 2°C and 8°C for stability
Incompatible Materials: Strong oxidizers, acids, bases, moisture, water

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established limit for substance itself; Methanol byproduct (OSHA PEL 200 ppm, ACGIH TLV 200 ppm)
Engineering Controls: Local exhaust ventilation, eyewash stations, emergency showers
Respiratory Protection: NIOSH–approved organic vapor respirators if ventilation inadequate
Hand Protection: Nitrile or neoprene gloves
Eye Protection: Safety goggles or face shield
Other Protection: Lab coat, chemical-resistant apron, closed footwear

Physical and Chemical Properties

Appearance: Clear, pale yellow liquid
Odor: Faint amine-like odor
Odor Threshold: Not determined
pH: Not applicable (hydrolyzes in presence of water)
Melting Point/Freezing Point: Below -30°C
Boiling Point/Range: Approx. 284°C
Flash Point: 130°C (closed cup)
Evaporation Rate: Not determined
Flammability: Flammable liquid
Upper/Lower Flammability or Explosive Limits: Not established
Vapor Pressure: Low at 20°C (approx. 0.03 mm Hg)
Vapor Density: Heavier than air
Relative Density: 1.02-1.04 g/mL at 25°C
Solubility: Partially miscible with water (hydrolyzes slowly), soluble in organic solvents
Partition Coefficient (n-octanol/water): Not determined
Auto-ignition Temperature: Not determined
Decomposition Temperature: Not determined
Viscosity: 25–35 mPa.s at 25°C

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions, sensitive to moisture
Polymerization: No hazardous polymerization expected
Conditions to Avoid: Heating, open flame, moisture, incompatible materials
Incompatible Materials: Strong acids, oxidizing agents, bases, water
Hazardous Decomposition Products: Methanol, formaldehyde, nitrogen oxides, silicon oxides

Toxicological Information

Likely Routes of Exposure: Inhalation, skin, eye contact, ingestion
Symptoms: Irritation to skin, eyes, upper respiratory tract; possible CNS effects if methanol inhaled/ingested
Acute Toxicity (Estimated): Oral LD50 (rat) > 2000 mg/kg; Skin LD50 (rat/rabbit) > 2000 mg/kg
Skin Corrosion/Irritation: Causes skin irradiation
Serious Eye Damage/Irritation: Causes serious eye irritation
Respiratory or Skin Sensitization: No data available; not expected to be sensitizing
Chronic Effects: Prolonged exposure may cause dermatitis, methanol byproduct neurotoxicity
Carcinogenicity: Not classified as carcinogenic
Mutagenicity: No specific data
Reproductive Toxicity: Not established for parent substance, methanol metabolite affects fetal development

Ecological Information

Ecotoxicity: Not classified as hazardous to aquatic life; hydrolysis releases methanol, which is toxic to aquatic organisms
Mobility: Expected to bind to soil or hydrolyze to silanols and methanol
Persistence and Degradability: Hydrolyzes slowly in water, silanol group degrades further in environment
Bioaccumulative Potential: Not expected to bioaccumulate
Other Adverse Effects: Avoid release to environment, methanol toxic to aquatic organisms in larger quantities

Disposal Considerations

Waste Disposal Methods: Dispose of in accordance with local, regional, and national regulations; incineration preferred at approved facility
Contaminated Packaging: Empty containers retain vapor, handle as hazardous waste, offer for recycling if possible after thorough cleaning
DO NOT: Dispose to sewer, surface water, or uncontrolled locations

Transport Information

UN Number: 1993
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: III
Proper Shipping Name: Flammable liquid, n.o.s. (Bis[3-(Trimethoxysilyl)Propyl]Amine)
Environmental Hazards: Not classified as marine pollutant
Special Precautions: Handle in accordance with applicable regulations, secure containers during transit

Regulatory Information

OSHA Hazard Communication Status: Hazardous chemical
TSCA status: Listed
DSL/NDSL (Canada): Listed
Labeling Requirements: Signal word, hazard pictograms, precautionary and hazard statements consistent with GHS
SARA 313: Not listed
California Proposition 65: Methanol produced, listed for reproductive toxicity
Other International Regulations: Check country-specific inventories for compliance