Product Name: Methylpropyldichlorosilane
Chemical Formula: C4H10Cl2Si
Synonyms: Dichloro(methyl)propylsilane, Propylmethyldichlorosilane
CAS Number: 13646-07-2
Manufacturer: Available upon request
Emergency Contact: CHEMTREC: 1-800-424-9300
Uses: Intermediate in silicone production, additive in chemical synthesis, laboratory reagent
Hazard Classification: Flammable liquid, Corrosive to skin and eyes, Toxic if inhaled and ingested
GHS Label Elements: Flame, Corrosion, Skull and Crossbones
Signal Word: Danger
Hazard Statements: Causes severe skin burns and eye damage; May cause respiratory irritation; Harmful if swallowed or inhaled; Reacts violently with water releasing hydrogen chloride gas; Can form explosive mixtures with air
Precautionary Statements: Avoid breathing vapors, Use only outdoors or in well-ventilated area, Wear protective clothing and eye protection, Wash thoroughly after handling
Symptoms of Exposure: Burning sensation, coughing, shortness of breath, skin and eye reddening, gastrointestinal distress
Chemical Name: Methylpropyldichlorosilane
CAS Number: 13646-07-2
Concentration: 98–100% by weight
Impurities: Trace amounts of trichloropropylsilane, methylchlorosilane derivatives
Inhalation: Remove person to fresh air, keep comfortable, administer oxygen if breathing is difficult, seek immediate medical attention
Skin Contact: Immediately remove contaminated clothing, rinse skin with copious amounts of water for at least 15 minutes, call a physician
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, continue rinsing, seek medical attention urgently
Ingestion: Rinse mouth, do not induce vomiting, give water if conscious, obtain medical help immediately
Most Important Symptoms: Burning pain, tissue destruction, difficulty breathing
Other Advice: Ensure medical personnel know the chemical involved and show the MSDS if possible
Suitable Extinguishing Media: Dry chemical powder, carbon dioxide, alcohol-resistant foam, DO NOT use water directly
Specific Hazards: Releases toxic hydrogen chloride and phosgene gases upon combustion, flammable vapor can travel distances and flashback, reacts violently with water
Fire-Fighting Equipment: Self-contained breathing apparatus, full protective clothing, fire-resistant gloves
Special Procedures: Cool containers exposed to flames with flooding quantities of water from a safe distance, stay upwind, avoid breathing fumes
Personal Precautions: Evacuate non-essential personnel, ventilate area, restrict access, wear chemical splash suit, goggles, gloves, and respirator
Containment Methods: Stop leak only if safe to do so, prevent run-off to sewers and waterways, dike spill with inert absorbent material such as vermiculite or sand
Cleanup Procedures: Use non-sparking tools, place absorbed material in sealed, labeled waste containers for disposal, clean area with inert absorbent, avoid water contact
Environmental Precautions: Prevent discharge into drains, surface and groundwater, notify authorities if environmental contamination occurs
Handling: Use only in well-ventilated fume hood or explosion-proof environment, avoid breathing vapors and contact with eyes or skin, prevent static build-up, use proper grounding and bonding
Storage: Store tightly sealed in a cool, dry, and well-ventilated area, away from sources of ignition, incompatible chemicals (moisture, water, alcohols, acids, oxidizers), keep container upright, protect from sunlight, segregate from food and feedstuffs
Special Storage Requirements: Use corrosion-resistant containers (glass or certain plastics), regular inspection of storage vessels, install gas monitors if possible
Exposure Limits: No OSHA PEL set, ACGIH TLV not established, minimize exposure as much as possible
Engineering Controls: Local exhaust ventilation, chemical fume hood, explosion-proof electrical equipment, emergency eyewash and safety shower access
Personal Protection: Chemical-resistant gloves (nitrile, butyl rubber), impervious lab coat, splash goggles or face shield, respiratory protection (organic vapor cartridge respirator or SCBA for emergencies), remove contaminated clothing immediately and launder before reuse
Hygiene Measures: No smoking, eating, or drinking in work area, wash hands and exposed skin thoroughly after handling
Appearance: Clear, colorless to pale yellow liquid
Odor: Pungent, irritating, acrid
Molecular Weight: 175.11 g/mol
Boiling Point: 117–120°C (243–248°F)
Melting Point: -58°C (-72°F)
Flash Point: 28°C (82°F) Closed Cup
Vapor Pressure: 20 mmHg at 20°C
Solubility: Reacts violently with water, soluble in most organic solvents
Density: 1.046 g/cm³ at 25°C
Evaporation Rate: Not available
Partition Coefficient (n-octanol/water): Not determined but expected to have high affinity for organic phase
Chemical Stability: Stable in tightly sealed container under dry, inert conditions
Reactivity: Rapid and violent hydrolysis on contact with water, alcohols, acids; generates heat, hydrogen chloride gas and silanols
Conditions to Avoid: Moist air, water, heat sources, sparks, open flames, direct sunlight
Incompatible Materials: Moisture, water, alcohols, oxidizing agents, strong acids and bases, amines
Hazardous Decomposition Products: Hydrogen chloride gas, methyl chloride, silicon oxides, phosgene (at high temperatures)
Acute Toxicity (Oral, Dermal, Inhalation): Moderate to high toxicity, LD50 (oral, rat): approx. 890 mg/kg; LC50 (inhalation, rat, 4 hr): approx. 300 ppm
Skin and Eye Contact: Severe burns, possible permanent eye damage or blindness; immediate discomfort, tissue destruction
Inhalation Effects: Irritation to mucous membranes, respiratory tract, fluid in lungs may develop with severe exposures
Ingestion Effects: Burns of mouth and gastrointestinal tract, pain, nausea, vomiting
Chronic Effects: Data limited, repeated exposure may lead to skin sensitization and respiratory irritation
Carcinogenicity/Mutagenicity: Not listed as carcinogen by IARC, NTP, OSHA; no evidence of mutagenic effects in standard tests
Ecotoxicity: Toxic to aquatic organisms, acute effects likely to fish and invertebrates, can cause long-term adverse effects in aquatic environments due to persistent acidification from hydrochloric acid release
Persistence and Degradability: Hydrolyzes rapidly in moist air or water forming silanols and hydrochloric acid; silanols may further degrade, hydrochloric acid lowers pH
Bioaccumulation Potential: Low bioaccumulation expected for degradation products
Mobility in Soil: Low due to rapid hydrolysis and adsorption of products to soil; mobile in environments lacking water
Other Adverse Effects: Forms corrosive mixtures in natural waters; risk of environmental damage increases with volume of uncontrolled release
Waste Treatment Methods: Must be handled as hazardous waste; neutralize carefully in controlled manner with sodium bicarbonate or lime, only by trained professionals; collect in corrosion-resistant containers
Disposal of Product: Incineration at licensed chemical waste facility permitted for organochlorine wastes; do not dump into drains, natural watercourses or soil
Disposal of Contaminated Packaging: Triple rinse containers, use appropriate solvent, render unusable; dispose of as hazardous waste
Regulatory Provisions: Comply with federal, state and local environmental control regulations for hazardous wastes
UN Proper Shipping Name: Methylpropyldichlorosilane
UN Number: UN 2987
Transport Hazard Class: 3 (Flammable liquid), 8 (Corrosive)
Packing Group: II
Labels Required: Flammable Liquid, Corrosive
Marine Pollutant: Yes
Environmental Hazards: Severe in case of water exposure; emergency response guide available from DOT
Special Precautions for User: Segregate from incompatible materials, avoid shipment with foodstuffs or publicly accessible areas, use original tight packaging, emergency measures required during transport accidents
OSHA: Hazardous chemical under Hazard Communication Standard (29 CFR 1910.1200)
SARA Title III, Sections 302, 304, 311, 312, 313: Listed for acute health and fire hazards, subject to reporting as toxic chemical (313) if quantities exceed threshold
TSCA Inventory: Listed
REACH (Europe): Registration duties apply, substance subject to restrictions under Annex XVII
Other Regulations: Subject to hazardous waste regulations under RCRA; restrictions on import/export under Rotterdam Convention; California Proposition 65 not listed as a carcinogen or reproductive toxicant
Workplace Labeling: GHS pictograms required, precautionary and hazard statements must appear on all containers, mandatory safety training for all personnel
