Chemists began exploring organosilanes like N-[3-(Trimethoxysilyl)Propyl]Anilin over 50 years ago trying to close the gap between organic and inorganic worlds. Tradeoffs between flexibility and strong adhesion often held back industries that demand durability, from coatings to construction. Research on this specific compound started in earnest as materials engineers looked for ways to improve surface bonds, especially when glass, ceramics, or metals had to meet compatible polymers. Early adopters saw value in the versatile structure of N-[3-(Trimethoxysilyl)Propyl]Anilin, leveraging its amine group and trimethoxysilane end to address chronic adhesion failures. Decades of incremental gains and collaborative projects between academia and manufacturing solidified its role: not fancy, but reliable and proven in real-world tests and manufacturing floors.
This organosilane acts as a coupling agent, adhesion promoter, and surface modifier. Its unique feature lies in bridging silicon-based surfaces with organic resins. This quality makes it a top choice for plenty of industrial formulations. Over the years, the versatility of this compound has drawn attention from automotive, electronics, aerospace, and building materials sectors. It doesn’t grab headlines, but ask any formulator how to keep glass fibers locked in polyester, or tackle moisture resistance in a fussy composite—the answer often points straight to N-[3-(Trimethoxysilyl)Propyl]Anilin.
This clear to pale yellow liquid usually comes with a faint ammonia scent, reminding you there’s an amine tucked in. Its molecular weight settles around 257 g/mol, which might look modest on paper, but delivers powerful effects on surfaces. With a density just above that of water (1.05–1.09 g/cm³), it flows smoothly without fuss in most production setups. It’s not flammable, but the methoxy groups will react with water, creating methanol in the process. Storage in dry, closed containers keeps its shelf life strong, avoiding that dreaded hydrolysis that saps performance. People working on shop floors know these details mean fewer surprises at scale.
Manufacturers list assay percentages above 98%. Purity at this level means surface treatments achieve the predictability factories demand. Labelling usually includes UN shipping codes, hazard pictograms, and batch information for traceability. The most reliable producers share detailed certificates of analysis, not only for peace of mind but for compliance with global chemical regulations. These technical pages anchor product quality in real numbers and hard data, which every process engineer or safety officer appreciates.
To produce N-[3-(Trimethoxysilyl)Propyl]Anilin, chemists usually lean on classic organic synthesis principles. Most routes start with an aniline precursor and a trialkoxy silane, running the reaction under mild heat and moisture-free conditions. Acid or basic catalysts help control the process, boosting yield while limiting byproduct formation. It isn’t always elegant or flashy, but the method has proven reliable at both research and commercial scales, offering consistent quality and cost control.
The methoxysilane group loves water; hydrolysis snaps those methoxy pieces off, replacing them with silanol groups. Those silanol groups grip glass, minerals, or metals, laying a chemical foundation for tough bonds. At the other end, the aniline group forms strong attachments to epoxy, polyurethane, or other polymeric chains. By tuning reaction time, solvent choice, or temperature, chemists adjust the balance of organofunctional and silane groups, chasing the sweet spot for each application. This adaptability keeps N-[3-(Trimethoxysilyl)Propyl]Anilin on innovation teams’ shortlists whenever a fresh challenge comes up in product development.
N-[3-(Trimethoxysilyl)Propyl]Anilin appears under various names, like Aniline, N-(3-(trimethoxysilyl)propyl)-, Silane coupling agent KH-550, or SCA-A10. Suppliers in China, Europe, and North America each market it under different brands, but the core chemical structure stays the same across catalogues. This handful of synonyms makes life easier for buyers and formulators trying to source supply across borders and regulations.
Handling any reactive silane involves respect for personal safety and environment protocols. Separate dry storage, use of protective gloves and goggles, and efficient fume extraction top the checklist in any facility working with the compound. Methanol forms during hydrolysis, posing a flammability and toxicity hazard if not properly contained. The best-run factories embed N-[3-(Trimethoxysilyl)Propyl]Anilin in their safety training, spill response drills, and chemical inventory audits. Meeting standards like OSHA in the United States or REACH in Europe isn’t an afterthought—it shows a real commitment to worker well-being and community protection.
If a market needs a strong, stable bond between an inorganic surface and an organic coating, this silane sees action. Manufacturing teams use it to treat glass fibers for reinforced plastics, boost adhesion in rubber compounds, improve corrosion resistance on metals, and prep mineral fillers for plastics. Electronic device makers add it to resin mixes for circuit boards. Specialty paint and coating suppliers include it to prevent peeling or blistering from moisture. Even advanced medical devices look to organosilanes for surface stability and biocompatibility. The footprint of this molecule stretches from mass production floor to research bench.
Material scientists push the boundaries of what these silanes can do, setting up side-by-side comparisons, durability trials, and failure analyses. Academic research, often in partnership with industry, has built a pile of peer-reviewed data tracking performance over time, in extreme temperatures, or aggressive chemical environments. Innovation rarely moves in leaps, but N-[3-(Trimethoxysilyl)Propyl]Anilin keeps earning its place thanks to its ability to solve old problems in fresh applications, from 3D printed materials to bio-compatible coatings for implants.
Safety scientists dig deep into toxicity questions, performing animal studies, workplace exposure assessments, and long-term monitoring. The amine portion of the molecule introduces some irritation risk to skin and eyes. Methanol, produced as a byproduct, brings its own well-known hazards. Studies point toward a need for strict exposure controls rather than blanket bans, and regulatory agencies publish handling guidance to help manufacturers and users avoid chronic exposure. With good process controls and monitoring, industries have shown that safe use remains achievable.
Product demand trends up with each new material innovation relying on hybrid interfaces, from smart windows and flexible displays to lightweight composites in transport and energy storage systems. Ongoing projects focus on reducing ecological impact, exploring green chemistry approaches to production and end-of-life options for silane-treated materials. More collaboration between researchers, suppliers, and manufacturers lines up fresh ideas for reducing hazards, recycling waste, and raising performance even further. The future of N-[3-(Trimethoxysilyl)Propyl]Anilin will likely ride on a blend of practical needs, sustainable progress, and scientific curiosity that has fueled its story so far.
Discovering a chemical like N-[3-(Trimethoxysilyl)Propyl]Anilin lands you right at the crossroads of function and possibility. Folks in laboratories gravitate toward this material for one reason: it connects things that usually would not stick together. On one end, its aniline group sits ready to team up with organic molecules. On the other, the silane end gets along with glass, metal, ceramics, and plastics. Blending those properties opens a range of practical uses, and industries latch onto that versatility to solve some tricky challenges.
Years spent working in materials science taught me how easy it is for fiber-reinforced composites to fall short if the resin does not lock tightly to the fibers. Throwing this silane compound into the mix makes equipment last longer and parts work more reliably. Engineers use it to treat glass or carbon fibers before resin pouring. That prep step gives real muscle to the final product, cutting down on breakage. Manufacturers of wind turbine blades, car parts, and even sports gear depend on this kind of treatment to stand up to harsh conditions.
Ask anyone who has needed, say, their car’s paint job to survive a blazing summer and a freezing winter. Silane coupling agents help paints and coatings hang on tight to surfaces that might peel, bubble, or crack under weather swings. Paint producers mix this molecule to strengthen the bond between pigment and metal or glass. The chemistry that lets a car door keep shining after years outside often starts with compounds like N-[3-(Trimethoxysilyl)Propyl]Anilin. In the adhesive world, the story runs much the same. It forms chemical bridges, keeping tiles stuck to concrete or laminate held fast to countertops—even when temperature and humidity shift more than you’d think possible.
Microchips and printed circuit boards rely on thin films and barrier layers to keep internal connections dry and corrosion-free. An effective primer comes from the silane family. Chemists apply N-[3-(Trimethoxysilyl)Propyl]Anilin to the surface before layering other materials. The result is a tougher, longer-lasting chip, which plays a bigger role than most people realize in how long a phone or laptop keeps working. This molecule lines up as a trusted helper in the search for electronics that last, rather than wind up in a landfill after a year or two.
Walk through an old building with stained, crumbling concrete and you’ll see the downside of untreated surfaces. Builders use silane coupling agents inside sealants and treatments for concrete. These compounds help water and salt run off rather than soak in and trigger decay. That extends the life of parking garages and bridges well beyond what untreated cement could manage. According to research published by the American Concrete Institute, silane-modified sealants slash the costs of repair and keep infrastructure safer for longer.
As companies look for ways to make their products perform better with fewer environmental side effects, silane chemicals find new niches. Smaller amounts can boost strength enough to let engineers cut down waste. That mindset flows from facts: materials that last keep more scrap out of the landfill, and fewer breakdowns mean less replacement. It turns out that practical, smart chemistry like this doesn’t just fill gaps between substances—it bridges the way to longer-lasting goods and less wasted resources.
Growing up, I learned that how you store something shapes how it holds up over time, whether it’s garden vegetables, medication, or even hardware in the garage. I’ve seen first-hand how cutting corners on storage can lead to moldy bread, faded paint, or spoiled supplements—money basically wasted. It’s easy to overlook the simple habits that protect the value and safety of what we buy.
Products respond to the environment where they spend their time. Heat will speed up chemical reactions, so medicine stored next to a bathroom heater breaks down and loses power. Moisture pushes food to spoil faster, even if it’s still sealed. UV light weakens plastic and medicine labels fade, making it tough to read important details. A bit of planning saves headaches and keeps money in your pocket.
Manufacturers recommend cool, dry, and dark storage conditions because science backs up the damage done by heat, humidity, and sunlight. Most pharmaceuticals benefit from storage temperatures below 25°C (77°F). Food—especially grains, spices, and snacks—stays fresh longer with humidity under 60%. Sunlight causes vitamins and scents to break down, so keeping things tucked away in closed cupboards or dedicated storage bins pays off. Data from the Food and Drug Administration show that up to 20% of medication failures link back to poor storage, not expiration.
Some materials come with specialized needs. Batteries last longer in a dry place far away from metal objects. Art supplies and adhesives work better on your next project if they skipped the summer heat. Cleaning chemicals should never mix and need a spot out of reach from kids and pets, again highlighting the value of basic storage habits.
During a long summer power outage, everything in the pantry took a hit. The chocolate chalked up, cans rusted, and medicine tablets stuck together—all because our kitchen heated up to nearly 90°F for days. That short spell taught me that a basement shelf or even a closet shelf, far from direct heat, can mean the difference between tossing and saving. It makes sense to invest in airtight containers or moisture absorbers. Simple silica packs or low-cost dehumidifiers help stretch the shelf-life for goods that matter most.
Choosing the right spot for each product makes a real difference. Refrigerators work for some medications, but accidental freezing wrecks insulin and other temperature-sensitive products. As for dry goods, a sealed plastic bin keeps bugs and moisture away better than the opened original packaging. Labeling containers with purchase or expiration dates helps busy families clear out old stock before it turns bad.
I’ve found it worthwhile to check original packaging for storage specifics. Trustworthy companies share that information right on the label. Medical professionals and pharmacists can offer advice for anything meant to be swallowed or spread on the skin. Product-specific storage guidance protects you, your wallet, and your peace of mind.
Storing products with care often feels like an extra chore, but the pay-off shows in longer-lasting purchases and fewer last-minute emergencies. A small shift in habit makes a bigger difference than people expect, both for health and home economics.
N-[3-(Trimethoxysilyl)Propyl]Anilin shows up in laboratories and on shop floors because it binds well to many surfaces and finds its way into coatings, adhesives, and functional materials. I’ve seen people treat silane-based chemicals casually, probably because the name doesn’t ring warning bells like “cyanide” does. Still, this stuff brings its own risks. Inhalation, skin contact, or splashing it in the eyes causes irritation and, over time, sensitization. Safety Data Sheets aren’t just paperwork; they spell out real problems folks run into. I once saw red, itchy skin after only a few splashes on the neck. Breathing in vapors isn’t uncommon around open containers either, and you tend to get coughs and headaches faster than most realize.
Haphazard storage never works with organosilanes. Keeping N-[3-(Trimethoxysilyl)Propyl]Anilin in a tightly closed, labeled container in a cool, ventilated place keeps accidents rare. Moisture eats away at the chemical and leaves your storage space sticky and risky. So, a dry space with locked cabinets or flammable storage lockers beats an open shelf every time. I always check that someone can reach an emergency shower or eye wash in minutes, not after a maze-like scramble through clutter.
Working with any silane, gloves make all the difference. I prefer nitrile—latex doesn’t last long against solvents or reactive chemicals. Safety goggles keep sudden splashes out of your eyes, and a decent lab coat or apron keeps skin protected. I’ve watched people skip respirators, thinking quick work means no problems, but vapor exposure adds up. A good-fitting cartridge respirator or local ventilation system really makes a dent in air quality. In a shared workspace, one careless person can ruin everyone’s day, so labeling everything and practicing what you preach keeps the team healthy.
Someone always drops a bottle or bumps a beaker. Preparation beats regret every time. I keep absorbent pads and neutralizing agents close by, and I don’t let anybody use a mop and bucket—the fumes only spread that way. Small spills soak up with vermiculite, scoop into a metal drum, and head for hazardous waste disposal. Larger messes call for evacuation and a call to the specialists. You don’t improvise your way through chemical spills.
Most accidents happen on people’s first day with a new chemical, or when someone starts cutting corners. Demonstrations beat lectures any day. I’ve watched seasoned lab techs run quick safety drills so everyone gets used to finding the eyewash, reading labels, and suiting up fast. Everyone, from new hires to veterans, needs refreshers every year.
A safer workplace grows from open talk about risks. I encourage folks to report close calls, not just disasters—I’ve learned more from stories about near-misses than official reports. Substituting less hazardous materials where possible makes a big difference, too. Sharing lessons learned in a group meeting and listening to every voice, from janitor to chemist, shrinks risks. Leadership has to deliver on promises for fresh PPE, working hoods, and real training—otherwise, safety talk never sticks.
Every molecule has its own story, from the way its atoms stick together to the weight it adds up to on the lab scale. Take common table salt. Sodium hooks up with chlorine in a straightforward, cube-shaped structure. It’s easy to visualize: a sodium atom and a chlorine atom form a tight bond, and the resulting molecule weighs just under 58.5 grams per mole. Not flashy, but incredibly important in the world of chemistry and beyond.
The shape and size of a molecule influence just about everything it does. Look at medicines. Aspirin molecules pack a benzene ring linked to both a carboxylic acid and an acetyl group—the arrangement lets it fight pain and swelling without much fuss. This specific structure, C9H8O4, isn’t just random. Its 180 grams per mole weighs in heavily when pharmacists measure out a dose. Subtle changes in the connections or shape can completely change how a compound behaves inside the body.
Experience in a chemistry lab teaches a few things fast. Even tiny tweaks in molecular structure can have huge effects. Isomers, for example, share the same atoms yet deliver totally different results. Glucose and fructose both carry the formula C6H12O6, but their structures set them apart in taste, energy, and use. Handling these chemicals means knowing the blueprint of their bonds, and weighing out just enough for reactions or experiments relies on knowing each one’s molecular weight.
Understanding a compound’s structure and weight isn’t just for scientists in white coats. Farmers look at the makeup of fertilizers to maximize crop yields. Manufacturers check polymer chains to make tougher plastics. Cooks rely on baking powder’s structure for that perfect cake rise, even if they don’t think about molecules in the moment. Nearly every product in the supermarket rides on the back of chemical makeup, whether it’s a safe preservative in bread or the active ingredient in shampoo.
Molecular weight also drives safety and environment decisions. Picture industrial solvents. Knowing both their molecular weight and structure keeps workers safe, helps emergency crews plan responses, and gives regulators a way to keep air and water clean. In pharmaceutical plants, balancing structure and weight lets drug makers hit strict quality standards, making sure every pill does exactly what it’s supposed to do.
Plenty of lessons come from history’s tougher moments. Leaded gasoline powered cars for decades, but the shape and weight of lead compounds caused pollution and health problems that linger. Switching to unleaded fuels relied on a scientific understanding of how different structures perform, what they leave behind, and how humans interact with them. Solutions in the modern world often start with mapping out molecules, using technology to predict properties, hoping to build safer and smarter compounds along the way.
Scientists now use advanced imaging, computer modeling, and mass spectrometry to dig deeper into chemical structures and weights. This helps speed up discoveries of new medicines and eco-friendly materials. It’s the backbone not only of discovery, but also of making sure what we use and trust every day is both safe and useful.
Getting silane chemistry right goes beyond textbook formulas. Hands-on experience in industrial labs teaches the real story. N-[3-(Trimethoxysilyl)propyl]aniline brings together an aniline functional group and a trimethoxysilane moiety. The combination helps it anchor onto fillers and fibers, lending chemical grip between otherwise unfriendly materials. Blending it with other silanes is common in specialty coatings, adhesives, and rubber manufacturing. This sort of mixing often helps engineers tweak how flexible, strong, or moisture-resistant they want their products to be.
Chemical compatibility doesn’t follow a one-size-fits-all rule. The amine on the aniline part of this compound can be touchy. In practice, it doesn’t get along with silanes that have reactive groups—like isocyanate or epoxy functionalities—unless the formulation is carefully managed. If you put an amino silane with an epoxy silane in the same can under basic conditions, they can start a reaction that releases heat or causes gelling, changing the pot life and shelf stability. Nobody on a production line wants to clean out their mixing tanks because of a runaway reaction.
With silanes bearing alkyl, vinyl, or phenyl groups, the story changes. These don’t try to react with the aniline group directly. Mixing usually goes smoothly, and the end blend behaves as expected. This pattern shows up across batches and across industries, from composite resin manufacturers to automotive suppliers.
The actual surface being treated shapes results as much as the chemistry of the product itself. For example, silica-filled rubber sticks better using a silane blend with amino and sulfur functionalities. I’ve seen lab teams add N-[3-(trimethoxysilyl)propyl]aniline to a cocktail of other silanes for this very reason: the multi-functionality creates more anchor points, especially for hybrid organic-inorganic surfaces.
Once you prepare a batch with mixed silanes, storage becomes a sticking point. Water vapor in the air triggers the methoxysilane groups to hydrolyze and form a network. This leads to gumming up your drums or losing some of the power during storage. To squeeze the most value out of a silane blend, keep it dry before use and mix just before applying it to the surface. Technical datasheets rarely emphasize this, but people who have watched an entire mixer seize up understand the pain of ignoring storage advice.
Cleaner chemistry comes with experience and records of what does or doesn’t work on the production floor. Large operations often set up small-scale pilot blends with automated monitoring, logging viscosity and heat changes as silanes are combined. In many cases, rigorous record-keeping uncovers surprising chemical quirks, such as unwanted cross-linking between supposedly stable silane systems, especially under warm, moist conditions.
Better training for technical staff pays off in less downtime and fewer recalls. Integrating knowledge from lab-scale experiments with the intuition built from years on the job bridges the gap between product development and production reality. As markets push for lighter, stronger materials that survive harsh use, demand for well-chosen silane mixtures will only grow. Every time people use these blends to solve new engineering challenges, those “compatibility” lessons get written into the next set of batch notes, building a library of practical solutions instead of abstract guidelines.
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![N-[3-(Trimethoxysilyl)Propyl]Anilin](/static/26ffdaf2-b05a-4718-b9a8-e71fecc06434/images/3d/n-3-trimethoxysilyl-propyl-anilin.gif)
| Names | |
| Preferred IUPAC name | N-[3-(Trimethoxysilyl)propyl]aniline |
| Other names |
Aniline, N-(3-(trimethoxysilyl)propyl)- 3-(Trimethoxysilyl)propyl-N-phenylaniline N-Phenyl-3-(trimethoxysilyl)propylamine N-(3-Trimethoxysilylpropyl)aniline |
| Pronunciation | /ɛn θriː traɪˌmiːθɒksiˌsaɪliːl ˈproʊpɪl ˈænɪlɪn/ |
| Identifiers | |
| CAS Number | 13822-56-5 |
| Beilstein Reference | 1462107 |
| ChEBI | CHEBI:132990 |
| ChEMBL | CHEMBL42968 |
| ChemSpider | 14346441 |
| DrugBank | DB21845 |
| ECHA InfoCard | ECHA InfoCard: 100.070.311 |
| EC Number | 232-453-6 |
| Gmelin Reference | 85336 |
| KEGG | C19598 |
| MeSH | C546673 |
| PubChem CID | 6911615 |
| RTECS number | GV7875000 |
| UNII | DF1A273M2B |
| UN number | UN3334 |
| Properties | |
| Chemical formula | C12H21NO3Si |
| Molar mass | 317.46 g/mol |
| Appearance | Colorless to pale yellow transparent liquid |
| Odor | Aromatic |
| Density | 1.06 g/mL at 25 °C |
| Solubility in water | slightly soluble |
| log P | 1.72 |
| Acidity (pKa) | 6.3 |
| Basicity (pKb) | 4.96 |
| Magnetic susceptibility (χ) | -72.53·10⁻⁶ cm³/mol |
| Refractive index (nD) | 1.4920 |
| Viscosity | 25 mPa·s |
| Dipole moment | 3.25 D |
| Thermochemistry | |
| Std molar entropy (S⦵298) | 527.6 J·mol⁻¹·K⁻¹ |
| Hazards | |
| GHS labelling | GHS07, GHS08 |
| Pictograms | GHS07,GHS08 |
| Signal word | Warning |
| Hazard statements | H315, H319, H317 |
| Precautionary statements | P261, P280, P304+P340, P305+P351+P338, P312 |
| NFPA 704 (fire diamond) | 1-1-0 |
| Flash point | 124 °C |
| Autoignition temperature | 287 °C (549 °F; 560 K) |
| Lethal dose or concentration | LD50 Oral - rat - > 2,000 mg/kg |
| LD50 (median dose) | LD50 (median dose): Oral - rat - 3,790 mg/kg |
| NIOSH | Not listed |
| PEL (Permissible) | 50 ppm |
| REL (Recommended) | 30 mg/L |
| IDLH (Immediate danger) | No IDLH established. |
| Related compounds | |
| Related compounds |
N-(2-Aminoethyl)-3-aminopropyltrimethoxysilane 3-Aminopropyltriethoxysilane 3-Glycidoxypropyltrimethoxysilane 3-Mercaptopropyltrimethoxysilane N-Phenylaminopropyltrimethoxysilane |
