Chemical Name: N-Dodecyltrichlorosilane
Synonyms: Dodecyltrichlorosilane, Trichlorododecylsilane
CAS Number: 4484-72-4
Recommended Use: Laboratory chemical, surface modifier
Manufacturer: Supplier details available through the purchasing channel
Contact Information: Emergency telephone number attached to the chemical label at storage location, accessible at all worksite stations
Address: Reference workplace chemical safety documentation
Hazard Classification: Corrosive to skin, severe eye damage, hazardous to aquatic life
Labeling Elements: Signal word: Danger; Hazard pictograms: Corrosive (GHS05), Health hazard (GHS08), Environmental hazard (GHS09)
Hazard Statements: Causes severe skin burns and eye damage; Reacts violently with water; Harmful if inhaled or in contact with skin; Toxic to aquatic organisms with long-lasting effects
Precautionary Statements: Keep away from moisture; Do not breathe fumes or vapors; Wash thoroughly after handling; Avoid release to the environment; Wear protective gloves, eye, and face protection
Chemical Formula: C12H25Cl3Si
Main Components: N-Dodecyltrichlorosilane (CAS: 4484-72-4) 98% or higher
Impurities: Trace chlorosilanes, residual solvents, total volatility less than 2%
Stabilizing Additives: No additional stabilizers
Other Hazards: Hydrolyzes with moisture, releasing hydrochloric acid fumes
Inhalation: Move person outdoors to fresh air, monitor for difficulty breathing, seek emergency medical attention if symptoms like coughing, chest tightness, or dizziness linger
Skin Contact: Remove contaminated clothing, wash area thoroughly for at least 15 minutes using soap and running water, call for medical help immediately
Eye Contact: Flush eyes gently and continuously with water for at least 15 minutes, holding eyelids open, do not allow victim to rub eyes, emergency medical attention needed promptly
Ingestion: Rinse mouth thoroughly, do not induce vomiting, never attempt to give anything by mouth to an unconscious person, call for poison control or medical intervention without delay
Advice to Doctor: Immediate decontamination, monitor for respiratory distress and pulmonary edema, watch for delayed effects due to hydrolysis product (hydrochloric acid)
Suitable Extinguishing Media: Use carbon dioxide, dry chemical, or foam, do not use water as it reacts violently
Specific Hazards Arising from Chemical: During fire, releases corrosive and toxic hydrochloric acid fumes along with silicon oxides; containers may explode if heated
Special Protective Equipment: Firefighters need self-contained breathing apparatus and full chemical-protective clothing
Emergency Procedures: Approach from upwind, evacuate personnel from downwind hazard, prevent runoff into drains and watercourses
Personal Precautions: Evacuate non-essential personnel, ventilate area, wear full protective equipment including eye and face guards, avoid inhalation or skin exposure
Environmental Precautions: Prevent product from entering soil, sewers, and surface water, notify local authorities if contamination possible
Containment and Cleanup: Cover spill with absorbent inert material (like sand or vermiculite), collect into labeled containers for disposal, avoid water contact to control hydrolysis reaction, ventilate affected area until all vapors dissipate
Safe Handling: Work in fume hood with air extraction, always handle under dry inert gas if possible, avoid creation of aerosols or fine droplets, ground containers and transfer equipment to prevent static discharge
Storage Conditions: Store tightly closed in dry, well-ventilated area, use corrosion-resistant packaging, keep away from incompatible substances such as water, alcohols, strong acids, or bases
Special Notes: Always keep moisture out of storage container, inspect containers regularly for corrosion or leaks, install spill containment trays under storage shelves
Exposure Limits: No occupational exposure limits established for this compound, control exposure to possible hydrochloric acid formed from hydrolysis (OSHA PEL for HCl: 5 ppm ceiling)
Engineering Controls: Use with local exhaust ventilation, keep workspace under negative pressure, use air filtration to remove hydrochloric acid vapors
Eye/Face Protection: Chemical splash goggles, face shield recommended
Skin Protection: Nitrile or butyl rubber gloves, full-length chemical-resistant clothing, avoid direct skin contact at all times
Respiratory Protection: If vapor exposure expected, use NIOSH-approved air-purifying half-face respirators with acid gas cartridges or positive-pressure supplied-air respirators for high concentrations
Hygiene Measures: Wash hands before breaks and at end of work, never eat, drink, or smoke in handling areas
Form: Clear to yellowish oily liquid
Odor: Acrid, pungent similar to hydrochloric acid
Melting Point: -14°C
Boiling Point: 330°C (with decomposition)
Flash Point: 132°C (closed cup)
Autoignition Temperature: No data for compound, decomposition likely before ignition
Vapor Pressure: Very low at ambient temperatures, increases with heat
Solubility: Reacts with water, soluble in non-polar solvents (hexanes, toluene)
Density: About 0.94 g/cm³ at 25°C
Partition Coefficient (Log Kow): No data; similar long-chain silanes have high Kow
pH: Not applicable (reacts with water)
Chemical Stability: Stable under recommended storage conditions, highly sensitive to moisture or humid air
Reactive Materials: Hydrolyzes rapidly with water or moist air, generates hydrogen chloride
Hazardous Reactions: Violent release of heat and corrosive gases with water or alcohols, incompatible with strong oxidizers
Decomposition Products: Upon hydrolysis forms hydrochloric acid, silicon dioxide, higher temperatures generate toxic fumes
Acute Toxicity: Harmful by inhalation, ingestion, or skin contact, can cause severe burns to skin, mucous membranes, and eyes
Irritation/Corrosivity: Rapid and severe to skin and eyes, can lead to permanent eye damage, scarring on skin
Inhalation Risks: Severe respiratory tract irritation, pulmonary edema possible
Chronic Effects: Prolonged or repeated exposure may exacerbate dermatitis or respiratory issues, not identified as carcinogenic by IARC or NTP
Additional Information: Main toxic effects due to release of hydrochloric acid during hydrolysis, which is corrosive to living tissues
Aquatic Toxicity: Highly toxic to aquatic organisms, risk of long-term adverse effects in aquatic environment
Mobility: Reacts with water rapidly, forms less mobile products which may persist in soil
Persistence and Degradability: Siloxane core remains after hydrolysis, poorly biodegradable in environment
Bioaccumulation: High risk due to hydrophobic long chain, persists in fatty tissues
Additional Ecological Risks: Releases corrosive byproducts that cause acidification of aquatic systems, should prevent any uncontrolled release into environment
Product Disposal: Treat as hazardous chemical waste, neutralize under controlled conditions, never dispose down drain or ordinary landfill
Container Disposal: Triple rinse and destroy containers by incineration or recycling under local regulations
Recommended Disposal Methods: Consult with licensed hazardous waste disposal contractor, neutralize under expert supervision before disposal, comply with all state and federal laws
UN Number: UN 2987
Proper Shipping Name: Trichlorosilane, liquid, n.o.s. (contains N-Dodecyltrichlorosilane)
Transport Hazard Class: 8 (Corrosive liquids); subsidiary risk 6.1
Packing Group: II
Label Requirements: Corrosive, keep separate from incompatible materials and foodstuffs
Special Precautions: Use dedicated corrosion-proof containers, emergency response guide accessible, handlers to use full chemical PPE
Marine Pollutant: Yes
TSCA Status: Listed on US Toxic Substances Control Act Inventory
OSHA: Considered hazardous chemical, subject to Hazard Communication Standard
SARA Section 313: Not specifically listed, but hydrochloric acid and related compounds may trigger reporting
REACH Registration: Registered substance in the European Union, subject to restriction for consumer use
Other Regulations: Subject to Canadian WHMIS, Australian AICS, Japanese ENCS, Chinese IECSC
Local Requirements: Handlers must have access to site-specific risk assessments, maintain audit trail of all transfers, and monitor compliance against country-specific chemical safety directives
