Product Name: N-Hexadecyltrichlorosilane
Chemical Formula: C16H33Cl3Si
Synonyms: Trichloro(hexadecyl)silane, Hexadecyltrichlorosilane
CAS Number: 5894-60-0
Recommended Use: Laboratory chemical, surface modification agent for glass and silicon
Supplier Information: Manufacturer and distributor details, including address and emergency contact phone number, should appear as per local regulations.
GHS Classification: Acute toxicity (oral, dermal, inhalation) – Category 3; Skin corrosion/irritation – Category 1; Serious eye damage/irritation – Category 1; Specific target organ toxicity (single exposure) – Category 3
GHS Label Elements: Danger pictogram, Signal word: Danger
Hazard Statements: Causes severe skin burns and eye damage; Fatal if inhaled; Harmful if swallowed or in contact with skin; May cause respiratory irritation
Precautionary Statements: Wear protective gloves, clothing, eye and face protection; Avoid breathing dust or fumes; Use only outdoors or in well-ventilated areas; Wash hands thoroughly after handling
Chemical Name: N-Hexadecyltrichlorosilane
Concentration: ≥ 97% by weight
Impurities: No significant impurities relevant to health hazard present in typical lab or industrial-grade material
Molecular Weight: 351.88 g/mol
Inhalation: Remove from exposure to fresh air immediately; Seek medical attention; Provide artificial respiration if not breathing
Skin Contact: Remove all contaminated clothing immediately; Wash thoroughly with soap and water for at least 15 minutes; Call a physician or poison control center
Eye Contact: Flush eyes with abundant water for at least 15 minutes, lifting eyelids intermittently; Seek medical help immediately
Ingestion: Do not induce vomiting; Rinse mouth with water; If person is conscious, give water to dilute; Seek medical assistance immediately
Suitable Extinguishing Media: Dry chemical, foam, carbon dioxide (CO2), or alcohol-resistant foam
Specific Hazards: Yields toxic and corrosive hydrogen chloride fumes and silicon oxides when burning; Containers can rupture from pressure buildup
Protective Equipment: Wear self-contained breathing apparatus and full fire protective suit; Approach from upwind side only
Firefighting Instructions: Keep run-off waters out of sewers and waterways; Cool containers with water spray from a safe distance
Personal Precautions: Put on chemical-resistant gloves, safety goggles, and an approved respirator; Ensure proper ventilation or evacuate area
Environmental Precautions: Prevent further leakage, spillage, or entry into drains, soil or water bodies; Report massive spills to local authorities
Spill Cleanup Methods: Absorb liquid with inert absorbent (sand, earth, vermiculite); Scoop into a chemical waste container; Thoroughly wash the contaminated area with water; Dispose of properly
Safe Handling: Work in a chemical fume hood; Avoid direct contact or inhaling vapor; Handle only with suitable protective gear
Storage Conditions: Store in original, tightly closed containers; Keep in a cool, dry, well-ventilated area; Store away from water, acids, alcohols, and moisture
Incompatibilities: Moisture/water (forms corrosive hydrogen chloride), oxidizing agents, strong bases, and alcohols
Engineering Controls: Chemical fume hoods, local exhaust ventilation
Occupational Exposure Limits: No established ACGIH, OSHA, or NIOSH limits, but control to lowest feasible exposure due to corrosive potential
Personal Protective Equipment: Nitrile or neoprene gloves, chemical splash goggles or face shield, full-body covering, suitable respiratory protection for airborne concentrations
Hygiene Measures: Do not eat, drink, or smoke during handling; Remove contaminated clothing promptly; Wash thoroughly after exposure
Appearance: Colorless to pale yellow liquid
Odor: Pungent, acrid, characteristic
Boiling Point: Approx. 348°C (658°F)
Melting Point: Approx. -4°C (24.8°F)
Flash Point: 122°C (closed cup)
Solubility: Reacts vigorously with water; soluble in non-polar organic solvents
Density: 0.95 g/cm3 at 25°C
Vapor Pressure: Low at room temperature
pH: Not applicable; reacts with water to form hydrochloric acid
Chemical Stability: Stable under dry, inert conditions
Conditions to Avoid: Moist air, humidity, water; contact with alcohols, amines, strong bases, oxidizers
Hazardous Decomposition: Hydrogen chloride gas, silicon oxides, carbon monoxide, carbon dioxide
Polymerization: Will not undergo hazardous polymerization
Likely Exposure Routes: Inhalation, skin and eye contact, ingestion
Acute Toxicity: Highly toxic by inhalation (may cause fatal pulmonary edema), causes severe skin burns and eye damage, harmful if in contact with skin or swallowed
Chronic Toxicity: Long-term exposure can cause dermatitis, respiratory system effects, possible chronic organ toxicity
Symptoms: Burning sensation, cough, difficulty breathing, redness and pain on skin and eyes, possible delayed lung injury
Aquatic Toxicity: Very toxic to aquatic organisms if released in large quantities; forms persistent and hazardous siloxanes/hydrolysis products
Persistence/Degradability: Hydrolyzes rapidly in presence of water to form long-chain silanols and hydrochloric acid
Bioaccumulation Potential: Expected for organic fragment due to hydrophobic tail
Mobility in Soil: Will adhere to soil; possible runoff of acid hydrolysis products with rainwater
Waste Disposal Methods: Collect and contain residue in approved containers; Send to licensed hazardous waste disposal facility; Do not discharge into natural waters or sewer systems
Contaminated Packaging: Triply rinse and render containers unusable; dispose of as hazardous waste
Regulatory Compliance: All waste handling must meet relevant local, regional, national, and international disposal regulations
UN Number: UN 2987
Proper Shipping Name: Trichlorosilane, alkyl substituted
Transport Hazard Class: 6.1 (Toxic substances), 8 (Corrosive substances)
Packing Group: I (great danger)
Shipping Label: Toxic, Corrosive
Special Precautions: Avoid all contact and transport in dry, temperature-controlled and ventilated containers
OSHA: Classified as hazardous per 29 CFR 1910.1200
TSCA Status: Listed
REACH Registration: Required for import or manufacture in Europe
SARA 313: Not specifically listed, but reporting recommended given toxicity
Other Regulations: Subject to transportation regulations due to toxicity and corrosivity; May trigger workplace air monitoring and environmental permitting for emissions or releases; Requires labeling and training under GHS
