Product Name: N-Octadecyltrichlorosilane
Chemical Formula: C18H37Cl3Si
Synonyms: Octadecyltrichlorosilane, OTS, n-Octadecyltrichlorosilane
CAS Number: 112-04-9
Recommended Use: Surface modifier for glass, silicon, and other materials in research and industrial settings
Manufacturer: Contact local supplier or trusted chemical distributor
Emergency Contact Information: See manufacturer’s emergency contact sheet or CHEMTREC for rapid assistance
Classification: Corrosive to skin and eyes, Acute Toxicity (Oral, Inhalation, Dermal), Specific Target Organ Toxicity (Single Exposure), Hazardous to aquatic environment
Pictograms: Corrosive, Health hazard, Environment
Signal Word: Danger
Hazard Statements: Causes severe skin and eye burns, may cause respiratory irritation, harmful if swallowed or inhaled, toxic to aquatic life
Precautionary Statements: Avoid breathing vapors, use only outdoors or in well-ventilated spaces, wash hands thoroughly after handling, avoid release to the environment, wear protective gloves, clothing, eye and face protection
Chemical Name: N-Octadecyltrichlorosilane
CAS Number: 112-04-9
Concentration: 98–100%
Impurities: Not expected at hazardous levels based on technical datasheets
Additives: None known
Inhalation: Move person to fresh air, keep warm and at rest, seek medical attention if symptoms develop, provide oxygen or artificial respiration if needed
Skin Contact: Remove contaminated clothing immediately, rinse skin under running water for at least 15 minutes, use emergency shower if available, seek medical advice, launder contaminated clothing thoroughly before reuse
Eye Contact: Flush eyes with water or saline for a minimum of 15 minutes, hold eyelids apart to ensure complete rinsing, seek immediate medical attention
Ingestion: Rinse mouth with water, give water to drink only if person is conscious, never induce vomiting, seek prompt medical attention
Notes to Physician: Material hydrolyzes in presence of moisture, can form hydrochloric acid; treat symptomatically
Suitable Extinguishing Media: Dry powder, carbon dioxide, foam; avoid using water directly as decomposition produces hazardous fumes
Unsuitable Extinguishing Media: Water streams or water fog
Specific Hazards: Releases corrosive and toxic hydrogen chloride, silicon oxides, possible flammable vapors on combustion
Protective Equipment for Firefighters: Full protective gear including self-contained breathing apparatus to protect against toxic gases, approach upwind
Special Precautions: Containers may rupture from pressure buildup, cool exposed containers using water spray
Personal Precautions: Evacuate non-essential personnel, ventilate area, avoid contact with eyes, skin, and clothing, prevent inhalation of vapors or dust
Environmental Precautions: Avoid entry to drains, sewers, water bodies; notify environmental authorities if significant spillage occurs
Methods for Containment and Cleaning Up: Contain spill with inert absorbent material such as sand or earth, collect residue in chemical waste container, use non-sparking tools, ventilate area thoroughly, dispose of waste according to local regulations
Decontamination: Wash spill area with copious amounts of water, avoid further contact
Handling: Use only with appropriate local exhaust ventilation, keep containers tightly closed, avoid formation of vapors, do not get in eyes, on skin, or clothing, open under fume hood if possible, handle in dry conditions with moisture-free equipment
Storage: Store in original container away from heat, moisture, direct sunlight, oxygen, or strong bases, keep container sealed when not in use, keep in a cool, dry, well-ventilated area, segregate from oxidizing and incompatible chemicals
Incompatible Materials: Water, moisture, alcohols, strong bases, oxidizers, amines; reacts violently with water
Occupational Exposure Limits: No ACGIH or OSHA established limits for this compound; use conservative limits for similar organosilanes
Engineering Controls: Use chemical fume hood for all operations, local exhaust ventilation mandatory for large-scale use
Personal Protective Equipment: Chemical-resistant gloves (nitrile or butyl rubber), splash goggles and full-face shield, lab coat or chemical suit, impervious footwear, use respirator if exposure risk present at higher concentrations
Hygiene Measures: Wash hands with soap and water after handling, never eat, drink or smoke while using product, remove contaminated clothing and wash before reuse
Appearance: Colorless to pale yellow oily liquid
Odor: Sharp, acrid, pungent
Molecular Weight: 389.93 g/mol
Melting Point: < 0°C
Boiling Point: 182°C @ 5 mm Hg
Flash Point: > 110°C (closed cup, estimate)
Solubility: Reacts with water, soluble in organic solvents (toluene, hexane)
Vapor Pressure: ~0.1 mmHg @ 20°C
Density: 0.97 g/cm³ @ 20°C
pH: Not applicable (hydrolyzes in water)
Viscosity: Similar to other long-chain silanes
Chemical Stability: Stable under dry, inert conditions, sensitive to moisture and aqueous environments
Conditions to Avoid: Contact with water, strong bases, heat, ignition sources, humid environments
Decomposition Products: Hydrogen chloride, silicon oxides, hydrocarbons
Reactivity: Violent hydrolysis with water releases corrosive and toxic gases
Polymerization: Not anticipated under normal storage and handling
Routes of Exposure: Inhalation, dermal, ingestion, ocular
Acute Toxicity: Harmful by ingestion, inhalation, skin absorption; can cause burns from hydrolysis products
LD50 (Oral, Rat): Not well defined; related silanes show acute toxicity at ~2 g/kg
Skin Corrosion/Irritation: Severe irritation and corrosion observed in animal models
Eye Damage/Irritation: Causes serious eye damage and burns
Respiratory Effects: Can cause respiratory tract irritation, cough, chest pain, difficulty breathing
Chronic Effects: Long-term exposure data limited, possible skin sensitization, dermatitis, respiratory irritation with repeated contact
Target Organs: Skin, eyes, respiratory tract
Aquatic Toxicity: Highly toxic to aquatic life, LC50 and EC50 values for related silanes fall in low mg/L range
Persistence: Hydrolyzes rapidly in moist environments, products may remain persistent
Bioaccumulation: Not expected to bioaccumulate significantly due to hydrolysis
Mobility in Soil: Rapidly hydrolyzes, limited mobility of parent compound
Other Adverse Effects: Toxic to aquatic organisms even at low concentrations, products of hydrolysis may cause acidification
Waste Disposal: Collect must be placed in tightly closed, labeled waste container, handle as hazardous waste subject to local, state, and federal regulations, do not discharge into drains or watercourses, consulting licensed waste disposal company best
Contaminated Packaging: Empty containers must be triple-rinsed, can retain hazardous residues; treat as hazardous waste
Recommended Methods: Neutralize residues following site safety protocols; incinerate under controlled conditions; verify destruction of hazardous byproducts
UN Number: UN 2987
Proper Shipping Name: Alkyltrichlorosilanes, N.O.S. (N-Octadecyltrichlorosilane)
Transport Hazard Class: 8 (Corrosive)
Packing Group: II
Labels Required: Corrosive label compulsory
Marine Pollutant: Yes
Special Precautions: Secure containers upright, protect from moisture during all modes of transport
Regulatory Information for Air and Road: Must comply with IATA, IMDG, ADR guidelines
TSCA Status: Listed on the U.S. Toxic Substances Control Act inventory
REACH Registration: May require registration in EU under Regulation (EC) No 1907/2006, check compliance status
OSHA: Hazardous chemical as defined by the OSHA Hazard Communication Standard
WHMIS Classification (Canada): Class E – Corrosive, D2B – Toxic if inhaled or ingested
SARA Title III: Not listed as an Extremely Hazardous Substance but general reporting applies
Proposition 65: Not listed
Other International Inventories: Included in most chemical inventories: EINECS/ELINCS (Europe), DSL/NDSL (Canada), ENCS (Japan), AICS (Australia), etc.
