Product Name: Phenyltrimethoxysilane
Synonyms: Trimethoxy(phenyl)silane, PTMS
CAS Number: 2996-92-1
Recommended Use: Chemical synthesis, surface modification
Manufacturer/Supplier: Provided upon request
Emergency Contact: Refer to manufacturer’s emergency number
GHS Classification: Flammable liquids (Category 3), Skin irritation (Category 2), Eye irritation (Category 2A), Specific target organ toxicity - single exposure (Category 3)
Label Elements: Flame, exclamation mark
Hazard Statements: Flammable liquid and vapor. Causes skin and eye irritation. May cause respiratory irritation.
Precautionary Statements: Keep away from ignition sources. Wear protective gloves, protective clothing, and eye protection. Use only outdoors or in a well-ventilated area. Avoid breathing fumes.
Other Hazards: May emit methanol upon hydrolysis, which can be toxic if inhaled or absorbed through the skin.
Chemical Name: Phenyltrimethoxysilane
CAS Number: 2996-92-1
Concentration: ≥98%
Impurities: Methanol (may be released during decomposition or hydrolysis), residual solvents below reporting thresholds
Inhalation: Move person to fresh air. Provide oxygen or artificial respiration if needed. Seek medical attention if symptoms develop.
Skin Contact: Remove contaminated clothing. Rinse skin with plenty of water for at least 15 minutes. Call a physician if irritation persists.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Get medical help for ongoing discomfort.
Ingestion: Do not induce vomiting. Rinse mouth and seek medical advice. Never give anything by mouth to an unconscious person.
Notes to Physician: Monitor for signs of methanol poisoning including headache, nausea, vomiting, and visual disturbances.
Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, alcohol-resistant foam
Unsuitable Extinguishing Media: Water jet (may spread fire)
Specific Hazards: Vapors may form explosive mixtures with air. Fire may produce carbon oxides, silicon oxides, methanol, and other toxic fumes.
Firefighter Protection: Wear self-contained breathing apparatus and full protective gear. Keep containers cool with water spray.
Special Procedures: Remove containers from fire area if safe. Use water spray to cool exposed surfaces.
Personal Precautions: Evacuate area. Ventilate space. Avoid breathing vapors. Avoid contact with skin and eyes. Remove ignition sources.
Containment: Prevent entry into waterways, drains, or confined areas. Dike and contain spill with non-combustible absorbent material such as sand or earth.
Clean-Up Methods: Collect spillage in suitable containers for disposal. Wash area with plenty of water after material is collected. Use spark-proof tools.
Environmental Precautions: Avoid release to the environment. Notify authorities in case of larger spill.
Handling Recommendations: Use only with adequate ventilation. Ground containers when transferring material. Wear personal protective equipment. Keep away from heat, sparks, and open flames.
Storage Requirements: Store in tightly sealed original containers. Keep in a cool, dry, well-ventilated place. Protect from moisture as hydrolysis releases methanol.
Incompatible Materials: Strong acids, bases, oxidizing agents, water/moisture
Specific Storage Hazards: Ensure containers remain upright and tightly closed. Use corrosion-resistant floors and shelves.
Occupational Exposure Limits: No established limit for parent compound. Observe methanol limits: OSHA PEL 200 ppm TWA, ACGIH TLV 200 ppm TWA, 250 ppm STEL for methanol.
Engineering Controls: Use local exhaust ventilation to reduce vapor buildup. Implement explosion-proof electrical equipment.
Personal Protection: Chemical-resistant gloves (nitrile, neoprene), splash-proof goggles, flame-resistant lab coat or apron
Respiratory Protection: Use organic vapor cartridge respirator if ventilation cannot be ensured.
Hygiene Measures: Wash hands and face thoroughly before eating or drinking. Remove and wash contaminated clothing before reuse.
Appearance: Colorless to pale yellow clear liquid
Odor: Characteristic aromatic and alcohol-like odor
Molecular Formula: C9H14O3Si
Molecular Weight: 198.29 g/mol
Boiling Point: 193–194°C
Melting Point: Not applicable (liquid at room temperature)
Flash Point: 50°C (closed cup)
Auto-ignition Temperature: 425°C
Vapor Pressure: 1 mmHg at 40°C
Relative Density: 1.06 at 20°C
Solubility: Reacts with water, miscible with most organic solvents
VOC Content: Not specified
Chemical Stability: Stable under recommended storage conditions
Hazardous Reactions: Hydrolyzes quickly with water or moisture, releasing methanol
Conditions to Avoid: Heat, sparks, flames, moisture, poor ventilation
Incompatible Materials: Acids, bases, oxidizers, water
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, silicon oxides, methanol
Acute Toxicity: LD50 oral (rat): 2100 mg/kg (methanol is produced upon hydrolysis, toxic by ingestion, inhalation, and skin absorption)
Inhalation: Irritating to respiratory system. High concentrations can cause headache, dizziness, nausea.
Skin Contact: Causes irritation, may cause dermatitis after repeated exposure.
Eye Contact: Causes severe irritation, pain, redness, and possible corneal damage.
Chronic Effects: Prolonged exposure to methanol: blurred vision, central nervous system effects, organ damage
Mutagenicity: No data for parent compound. Methanol considered not mutagenic at typical exposure levels.
Carcinogenicity: Not classified as carcinogen by IARC, NTP, OSHA.
Ecotoxicity: Product is not classified as hazardous to the aquatic environment, but methanol produced upon hydrolysis is toxic to aquatic organisms.
Persistence and Degradability: Hydrolysis produces methanol, which biodegrades readily.
Bioaccumulation Potential: Low, both compound and methanol degrade and do not bioaccumulate significantly.
Mobility in Soil: Hydrolyzes to methanol and silanols, which have high mobility in soil; can leach to groundwater.
Other Effects: Discharges may contribute to chemical oxygen demand (COD) in receiving waters.
Waste Treatment Methods: Dispose in accordance with federal, state, and local regulations. Incinerate in a chemical incinerator equipped with afterburner and scrubber.
Container Disposal: Empty containers may retain product residue and vapor, handle as hazardous waste.
Special Precautions: Do not pour down drains or release to environment. Label and treat waste as flammable and toxic.
UN Number: UN 1993
Proper Shipping Name: Flammable liquid, n.o.s. (contains Phenyltrimethoxysilane)
Hazard Class: 3 (Flammable liquid)
Packing Group: III
Labels: Flammable liquid
Marine Pollutant: No
Special Precautions for User: Keep away from heat, secure containers.
OSHA Hazard Communication: Hazardous chemical
SARA 313: Methanol is listed; observe reporting requirements due to hydrolysis potential.
TSCA Inventory: Listed
REACH Status: Complies with applicable REACH requirements
California Proposition 65: Methanol is listed as a developmental hazard
Other Regulations: Compliant with international transport and chemical safety requirements. Verify with local regulations.
