Every chemical has a backstory that’s bigger than lab notes and patents. Tris-[3-(Trimethoxysilyl)Propyl]Isocyanurate doesn’t show up out of nowhere. Materials scientists recognized decades ago that silicone chemistry changed the way we could make things stick, flex, and endure. Organosilanes started seeing action in the mid-20th century, opening new doors for adhesives, coatings, and composites. Linking silicon to organic frameworks unlocked real-world improvements in durability—think glass fibers in construction, car parts, or wind turbine blades. With the hunt on for better crosslinkers and surface modifiers as polyurethanes, rubbers, and plastics swept through industry, isocyanurate derivatives offered a new molecule for researchers. Over time, chemists at academic labs and companies like Dow Corning explored trifunctional compounds, searching for the holy grail: strong bonds, chemical resistance, and process efficiency in one package. Today’s isocyanurate silane is the result of this persistent, creative work.
Tris-[3-(Trimethoxysilyl)Propyl]Isocyanurate belongs to the family of organosilicon compounds, combining a silane backbone with an isocyanurate ring. What jumps out about it is the triple silane arms, all anchored on a central core, each sporting reactive methoxy groups. I remember mixing this stuff with resins during test runs at the bench—sharp odor, but the clarity of the end product after curing stuck with me. Its trimethoxysilyl groups react with water or moisture to produce strong siloxane bonds; that’s what delivers its clout in surface treatment and as a crosslinker. The isocyanurate core stands up to high heat and tough conditions. Anyone putting together products that fight off weather, paint chips, or high temperatures looks twice at this compound.
Pour a bit on a glass plate and you see a colorless to pale yellow liquid, slightly viscous—almost syrupy. Its molecular weight tips the scale at around 633 g/mol. Don’t expect much action around room temperature, but show it some moisture and those methoxysilane arms wake up fast, causing hydrolysis and bond formation. It flashes a boiling point upwards of 270°C (decomposes instead of truly boiling), which opens opportunities to use it in manufacturing steps demanding heavy-duty processing. From a chemical angle, it’s got that triple-branch motif thanks to the isocyanurate ring, delivering rigidity plus options for greater crosslink density. Handling and measurement take a serious touch—like all silanes, it spoils in damp air and gels up. Storage in dry, airtight containers is non-negotiable.
Industry expects clarity when it comes to labeling. You want purity upwards of 98%. Labels must declare the precise chemical identity, potential impurities, and batch numbers for traceability. I’ve seen how labels save hours chasing down issues if a batch isn’t quite right. Technical datasheets usually spell out recommended storage conditions, handling instructions, shelf life (often pegged at 12 months sealed and dry), and packaging—metal drums or high-density polyethylene bottles keep air out. Anyone prepping formulations for external clients also shares safety data: flash point, recommended PPE, and strong cautions about mixing with water or humid air. There’s no wiggle room for vague specs here. If particulate matter or other silane variants show up on a COA (certificate of analysis), that shouts trouble for whoever ends up curing or blending that batch.
The backbone of this compound’s production comes from silane chemistry. Traditionally, the process grafts trimethoxysilane groups onto an isocyanurate ring using a well-planned alkoxysilane functionalization. Most industrial reactors use a solvent-based route, starting with cyanuric acid or isocyanuric chloride. The route involves reacting these with 3-chloropropyltrimethoxysilane, supported by a base catalyst to promote substitution. Temperature control makes or breaks yield: too low, and the reaction crawls, too high, and unwanted by-products multiply. After reaction completion, purification hinges on vacuum distillation and, sometimes, column chromatography. In my experience, handling the raw mix is always messier than anticipated—volatile methanol builds up, so closed loops and scrubbers save both yield and the environment. Batch tracking and tight process pressure control save real money over sloppy runs.
What sets this compound apart comes down to the silane arms. On contact with water, those methoxy groups turn into silanol, generating methanol and enabling condensation reactions. Link-up with glass, metals, ceramics, or even certain plastics becomes possible, forming robust siloxane bridges. In lab tests with epoxy or polyurethane systems, it created tighter, more durable materials, especially after exposure cycles to temperature swings or humidity. Chemists tweak reactivity by swapping methoxy for ethoxy or other alkoxy groups if slower hydrolysis is needed. Attaching other functional groups—vinyl, amine, or glycidyl—offers further fine-tuning, helping the compound fit into adhesives, sealants, or toughened composites. It’s not just theoretical: many of the best protective coatings around count on this chemistry for their staying power.
Chemists and marketers have never settled on just one name. You’ll run into names like Tris(3-trimethoxysilylpropyl)isocyanurate or 1,3,5-Triazine-2,4,6-trione, tris(3-(trimethoxysilyl)propyl) derivative across technical literature, SDS documents, and online supplier catalogs. The product numbers from different vendors—momentive, Evonik, Shin-Etsu, and others—can take some detective work to untangle. For anyone ordering in bulk, double-checking exact CAS numbers (chemsafety.com likes 26115-70-8) has saved more than one purchasing manager a nasty surprise after a late-night internet order.
Silanes pose a health risk if handled carelessly. The methoxy part liberates methanol when it reacts with water, and methanol brings both flammability and toxicity. Splash into the eyes or inhale the vapor, and it gets serious—respirators and splash goggles become a must in real production settings. I once forgot to swap out a glove and noticed an odd numbness in my fingers—not one of my prouder moments. Strict lockout, tag-out protocols around storage drums keep accidental exposure down. Industry guidelines require full disclosure of inhalation, ingestion, and skin contact hazards in the SDS. OSHA and REACH rules apply, with permissible exposure limits for methanol underscored in training. Regular air monitoring, good ventilation, and quick-spill response are part of the routine, not afterthoughts.
Most people never realize how often they benefit from silane chemistry. Look at wind turbines slicing through gales, solar panels on a roof, or composite bridges with slender lines, and this compound often plays a part. In my own fieldwork alongside engineers, adding this isocyanurate silane to fiberglass sizing improved both wet-out during lamination and the sticking power after weeks in the sun or rain. The compound sees action in high-performance adhesives, weatherproof coatings, automotive parts, and even 5G telecommunications gear. Used right, it toughens hybrid resins against heat, water, and salt. I’ve seen construction companies cut back site repairs and warranty calls after moving to silane-modified systems. Electronics manufacturers, always worried about reliability across temperature swings, now ask SMC and PCB suppliers about silane additives.
The past decade has brought a surge in research papers probing the bond strengths, corrosion resistance, and environmental footprint of silane-modified materials. Collaborations between universities and industry labs aim to optimize these compounds for lower VOC profiles and longer working times. In the lab, tweaking the isocyanurate core or the trialkoxysilyl side groups pushes the envelope for fire resistance and mechanical flexibility. Journals highlight the performance of silane hybrids in automotive and aerospace, and patent filings show steady interest in new surface-activating chemistries. Green chemistry has gained relevance, with pressure mounting to develop waterborne or solvent-free versions without giving up on performance. Startups and established firms alike pursue custom formulations so new infrastructure projects can hit ever-tighter safety and durability specs.
No review is complete without the unvarnished truth about hazards. Most lab results tag the parent isocyanurate ring as low in toxicity, but the side chains matter—trimethoxysilane can hydrolyze to release methanol, a known neurotoxin. Epidemiological data remain thin, especially for long-term, low-level workplace exposures. Risk assessment studies I’ve seen urge extra caution in poorly ventilated areas or during mixing phases where hydrolysis releases byproducts suddenly. Data points to a low risk for consumers who use finished goods, but no room for sloppiness during mixing, shipping, or disposal. Toxicity tests on aquatic life have triggered more scrutiny of process waste streams, nudging producers to tighten effluent standards. Safety reviews highlight the need for continuous research: better personal monitoring technology, more transparent impurity reporting, and expanded chronic exposure studies in the years ahead.
The chemical world never stands still. As green design and sustainable manufacturing gain ground, pressure is mounting to source, use, and dispose of specialty silanes with less risk and lower footprint. R&D labs have started exploring bio-based feedstocks for both the isocyanurate and silane portions. The hunt for higher yield syntheses with fewer byproducts gets driven by both regulatory agencies and clients tired of hazardous waste fees. Electronics and automotive giants now ask for lifecycle impact audits before approving new materials. Markets keep evolving—flexible displays, lightweight composites in e-mobility, and prefab construction will drive the demand for ever-tougher, smarter coupling agents. As climate and supply shocks shape industry, it’s become clear that advances in silane chemistry will ripple far beyond the lab bench. If researchers, regulators, and producers can collaborate on smarter, safer, greener variants, this one compound stands ready to power the next wave of innovation across sectors that touch daily life.
Tris-[3-(Trimethoxysilyl)Propyl]Isocyanurate, a mouthful to say, carries a lot of weight in fields where materials have to last and stick together. In coatings and paints, surface technology has come a long way through the use of silane-based chemicals. This compound gets noticed because it connects organic and inorganic materials better than most. The result is not just a stronger bond—it's coatings and adhesives that shrug off water, chemicals, and extreme temperatures. As someone who dabbles in DIY projects, I’ve seen how some protective coatings peel after a single winter while those treated with better bonding agents stay intact year after year.
Talk to anyone building cars, electronics, or skyscrapers. Weather, pressure, and time find every weak spot. That’s where this silane-based compound steps up. In electronics, a circuit board might see heat, dust, and humidity in a single day. Manufacturers use this material to prepare surfaces, ensuring that layers grip each other. This keeps chips, resistors, and contacts from loosening. In the construction world, glass and concrete rarely want to stick together for decades. With this compound, treated surfaces hang on tightly, delivering safer buildings and longer lifespans for critical infrastructure. I’ve seen firsthand how tile adhesives using advanced silane chemistry make the difference between cracked grout and a perfect finish after years of foot traffic.
Regulations keep getting stricter on what can go into adhesives and coatings. Old-school chemicals brought great performance but raised flags around toxic release—think solvents and heavy metals. This isocyanurate-based silane doesn’t just improve how things hold; it helps manufacturers meet European REACH standards and VOC limits. That speaks to safer products in schools, offices, and homes. Industry insiders report fewer product recalls tied to this chemical class because the chemistry allows lower emissions without giving up reliability. As a parent, that level of safety matters—nobody wants harmful chemicals in their living room paint or on the toys in their kid’s room.
Nothing in manufacturing comes without trade-offs. This compound asks for careful handling—proper mixing, curing time, and temperature control make all the difference in performance. Costs run higher than commodity adhesives or coatings, which can put some small businesses on edge. As demand rises in sustainable construction, economies of scale might help. Universities and R&D departments continue to look at ways to simplify handling and cut cost, but right now, skilled workers play a big role in successful results.
Companies face mounting pressure to make products last longer and leave a smaller environmental footprint. Tris-[3-(Trimethoxysilyl)Propyl]Isocyanurate makes that possible for many applications. To lower production costs, the industry can look to automation—pre-measured mixing, robotic dispensing, and better surface prep help reduce waste and speed up work in factories. Funding more research into low-cost, lower-toxicity alternatives might offer an answer for the budget-conscious without losing the benefits. Public awareness and transparency in ingredient safety can help people make informed choices too, whether they're sourcing for a factory or looking to refinish their basement floor.
This chemical tends to show up in labs or factories aiming to make plastics and coatings stronger, last longer, or stick to surfaces better. I’ve crossed paths with it during some R&D stints, and over time, you realize the slicker your workspace procedures, the fewer surprises you'll face. That stuff packs some risks if handled with a casual attitude. Eyes, skin, lungs—none of them appreciate exposure.
Gloves, goggles, and a lab coat often sound like clichés told to every rookie. But those warnings come from lessons, not theory. Latex or nitrile gloves usually get the job done, as the compound shouldn't seep through the barrier if you don’t leave it on for hours. Chemical splash goggles save you from a rough afternoon or worse, a lifelong eye issue. Open-toe shoes or bare arms around chemicals? Not worth shaving off five seconds from your routine.
Ventilation goes far beyond a window cracked open. Fume hoods act as real heroes for these situations. In closed, poorly-ventilated spaces, vapors can sneak up, irritate your throat, trigger coughing fits, and in bad cases cause longer-term health effects. Even in small quantities, isocyanurates can take a toll if you give them a chance to linger in the air.
Mishaps don’t always wait for supervisors. Having spill kits—pads, absorbent granules, neutralizers—within arm’s reach makes every bit of difference. I remember a colleague ignoring a small splash. Next thing we knew, the rest of the bench had a milky film, and the air grew sharp. Being quick and methodical with cleanup sets apart those who simply know the rules from those who live by them.
Rushing into mixing unknowns in the name of efficiency holds more risk than reward. This compound reacts poorly with acids, water, and bases. Heating it up in a closed container? You could build up pressure fast and sudden. Even regular maintenance folks should pause and check labels before draining or disposing of solutions.
No one should get asked to use specialized chemicals if they don’t understand the procedure. Onboarding shouldn’t end with a paperwork signature. Actual walk-throughs, even for old-timers, help reinforce what matters. In my own experience, mistakes rarely stem from malice—most happen when someone assumes they remember it all from six months ago.
Pouring waste down the drain feels fast and clean, but nothing good comes from sending isocyanurate residues into wastewater systems. Proper containers with clear labels steer clear of confusion. Many workplaces post laminated guides right by the exit or on bins so nobody has to track down a manual.
Nobody makes it through an entire career in chemical handling without leaning on others. It pays to watch out for coworkers, give reminders, and double-check labeling and storage. Building a culture that treats risk as everybody’s problem lowers accidents, builds trust, and actually saves time, not just paperwork.
Anyone handling chemicals like Tris-[3-(Trimethoxysilyl)Propyl]Isocyanurate—let’s shorten that to TTPI—knows storage isn’t just a formality. Mixing up safety can lead to damaged property or worse, health issues that stick around. TTPI belongs to the class of organosilanes, a group known for both their industrial usefulness and their quirks in storage.
Having had chemicals leak in the past, I’ve seen firsthand what poor storage can mean. Silane compounds react with moisture in the air, producing methanol as they break down. Keeping TTPI in a dry, cool space goes beyond ticking boxes. Methanol gets into the air, creates pressure risks in sealed containers, and can impact anyone opening the lid, even if just for a quick sample.
OSHA points out that methanol is toxic. Short-term exposure burns the eyes and lungs; longer exposure attacks the nervous system. Every time TTPI reacts with humidity in storage, methanol adds to the hazard pile. I learned in the field: respect these risks, and you avoid emergencies and liability.
The best practice: find a spot out of sunlight, away from direct heat, and dry as a bone. Store TTPI in containers made from materials that won’t interact with it—high-density polyethylene or steel lined with the right coatings. Glass jars don’t keep out moisture, and thin plastics break down over time.
A climate-controlled storeroom makes all the difference. Installing dehumidifiers turns out cheaper in the long run than scrapping a whole drum of contaminated chemical. Digital humidity monitors let you catch problems before they grow—something old-style storage just didn’t allow.
Labels need to spell out the chemical, concentration, date received, and hazard warnings. I’ve seen even experienced techs fumble when faced with faded or half-peeled tags. Good labeling isn’t just about compliance; it speeds safe handling. Keep an updated material safety data sheet (MSDS) onsite and review it with your team every quarter. These sheets get updated as new risks are discovered.
Regular inspections matter. Checking drum conditions, seals, and inventory saves more product than any after-the-fact clean-up crew. Any sign of water inside the storage area—condensation, plumbing leaks, or open vents—ruins months of careful planning. I once saw a small roof leak destroy $15,000 of inventory overnight.
Never store TTPI close to food, animal feed, or pharmaceuticals. Carrying forward the mistake of “temporary” storage invites contamination and regulatory headaches. Even trace amounts can throw off whole batches, leading to returns and business losses.
Investing in spill kits and emergency eyewash stations used to sound like overkill to me. Then I watched a co-worker get splashed—minutes made the difference in recovery.
Training makes or breaks a chemical storage system. Bringing in a consultant might sound expensive, but spreading knowledge among the whole staff saves more cash and keeps everyone safer. Smart organizations cycle out older inventory and use first-in, first-out systems. This keeps the oldest TTPI moving out, reducing the risk of surprise reactions or container failure. No piece of automation replaces walking the aisle and checking with your own eyes and hands.
Tris-[3-(Trimethoxysilyl)Propyl]Isocyanurate is quite a mouthful, but beneath the complicated name lies a structure with real-world muscle. Imagine starting with an isocyanurate core: a six-membered ring built from three nitrogen and three carbon atoms, each carbon linked by an O atom, forming a solid backbone. Chemists care about this ring because it resists heat and many chemicals. If you’ve ever worked on composite materials or specialty adhesives, seeing “isocyanurate” usually signals trustable toughness.
Attached to each nitrogen on that ring is a 3-(trimethoxysilyl)propyl group. Picture three arms sticking out, each made of a three-carbon chain. At the end of each, there’s silicon surrounded by three methoxy groups (—OCH3). This part cannot be overlooked—literally and chemically. In practical terms, those arms give the molecule its power to bond to both organic resins and inorganic surfaces like glass or metals. The “trimethoxysilyl” head tends to react with water or surfaces, leading to strong covalent bonds that don’t quit under pressure.
Anyone who’s ever mixed up a batch of resin for a repair job or worked on a high-performance coating knows you need more than just stickiness—materials should handle heat, moisture, even mechanical stress. This compound often makes an appearance in demanding products because the isocyanurate ring stands strong while the trimethoxysilyl groups crosslink with a wide variety of surfaces. That means products last longer and work harder, saving money and cutting down on waste.
I’ve seen firsthand how crucial these crosslinking agents are in industry. At a company I worked with, we struggled with adhesion problems between resin and glass. Swapping in a silane agent like this made all the difference. The chemical structure isn’t just a detail on a data sheet—it dictates how things hold up in cars, buildings, and electronics. Companies lean on real evidence; published research shows these molecules contribute to higher tensile strengths and better resistance to environmental breakdown.
Of course, nothing is perfect. Handling chemicals like this calls for respect. Trimethoxysilyl groups hydrolyze in humidity, and the resulting methanol isn’t exactly harmless. Smart manufacturing means providing proper ventilation, good training, and safer storage. What’s more, tracking exposure levels keeps workers healthy—a point highlighted by recent health and safety studies in the coatings sector. Some producers now look for ways to balance performance with reduced impact, like using more precise dispensing systems or developing new molecules that deliver durability without hazardous byproducts.
Tris-[3-(Trimethoxysilyl)Propyl]Isocyanurate’s structure does more than fill a slot on a chemical chart. Its carefully chosen components reflect decades of chemical progress and real need for products that don’t fail when the pressure’s on. Scientists and designers continue to tweak these structures to achieve ambitious targets in environmental health and product reliability. Anyone interested in better, safer materials ought to keep an eye on both the molecular details and the way they translate into performance.
Anyone who’s worked with composite materials, paints, or adhesives has probably handled silane coupling agents. These aren’t just obscure chemistry—they shape how well surfaces bond, how strong a final product feels, and how long things last under tough conditions. Among the rising chemistries, Tris-[3-(Trimethoxysilyl)Propyl]Isocyanurate keeps getting noticed, partly because its structure isn’t like your everyday silane. Blending it with other silanes isn’t just about whether molecules get along—it’s about real money spent on product life and reliability.
This isocyanurate-based silane brings three reactive arms (the trialkoxysilyl groups) and a central core that resists hydrolysis and heat. Plenty of times, projects call for mixing silane types: Some reinforce glass fibers, others seal minerals or bridge organic with inorganic materials. I remember an industrial flooring job where using a single coupling agent made tiles pop loose in months. Once we started blending—using a little isocyanurate silane with a simpler aminosilane—we got twice the peel strength and no callbacks for years.
Mixing Tris-[3-(Trimethoxysilyl)Propyl]Isocyanurate with other silanes isn’t free of risks, but published data and manufacturer guides show it works alongside most traditional agents. Its compatibility relates to the alkoxysilane parts, which react similarly to comparable trimethoxysilanes and play nice during hydrolysis and condensation. Heat stability goes up, water resistance improves, and you often get a broader range of successful applications—from tire cords to electrical encapsulants.
No chemical mix is perfect. Stirring multiple silanes together in water? Watch for premature gelation or unpredictable curing, especially if the pH isn’t managed. Silane blends can form byproducts that skip out on the job, sticking to glass or mineral surfaces in weak patches or clumping into micro-defects. Side reactions can sabotage adhesion if silanes compete, especially if mixing acidic and basic agents. I’ve learned from formulating epoxy coatings that it’s not just about pouring together what looks right—it’s controlling order of addition, concentration, and mixing speed.
There’s also a real-world impact from “invisible” factors like storage conditions. Moisture sneaks into drums and can trash shelf life by sparking pre-curing. Premixed blends should ship dry and see use within a few months if you want to preserve their value.
Practical fixes start with following technical data sheets from producers—not blind faith, but honest trial. Test individual and combined silanes at lab scale. Check for clarity, curing time, and adhesion with your real formulation. Lean into tools like FTIR or TGA to see how blends change over time. If you spot separation, haze, or a loss of strength, tweak ratios and mixing order. Sometimes, holding one silane just under its maximum loading spots the sweet spot.
The EU and U.S. regulatory frameworks have pushed clearer labeling and safer handling in recent years, so ask suppliers how their chemistries stack up in multi-silane systems. After all, finding the best compatibility between Tris-[3-(Trimethoxysilyl)Propyl]Isocyanurate and traditional silanes means less waste, stronger bonds, and products that hold up under real-world pressures. Those outcomes bring value way beyond the lab.
| Names | |
| Preferred IUPAC name | 1,3,5-Tris[3-(trimethoxysilyl)propyl]-1,3,5-triazinane-2,4,6-trione |
| Other names |
Tris[3-(trimethoxysilyl)propyl] isocyanurate Isocyanuric acid, tris(3-(trimethoxysilyl)propyl) derivative TMSPI Tris(3-(trimethoxysilyl)propyl)isocyanurate |
| Pronunciation | /ˈtraɪs θriː traɪˈmɛθɒk.siˌsɪlaɪl ˈproʊpɪl aɪˌsoʊˈsaɪə.njʊˌreɪt/ |
| Identifiers | |
| CAS Number | 26115-70-8 |
| Beilstein Reference | 3562312 |
| ChEBI | CHEBI:83198 |
| ChEMBL | CHEMBL4296741 |
| ChemSpider | 7874709 |
| DrugBank | DB11247 |
| ECHA InfoCard | ECC InfoCard: 100.218.342 |
| EC Number | 214-668-5 |
| Gmelin Reference | 728665 |
| KEGG | C17896 |
| MeSH | tris(trimethoxysilylpropyl)isocyanurate |
| PubChem CID | 102108766 |
| RTECS number | TZV6221530 |
| UNII | OMN8SN8U7Y |
| UN number | UN3334 |
| CompTox Dashboard (EPA) | DTXSID0067500 |
| Properties | |
| Chemical formula | C24H57N3O12Si3 |
| Molar mass | 879.15 g/mol |
| Appearance | Colorless to light yellow transparent liquid |
| Odor | Odorless |
| Density | 1.16 g/cm3 |
| Solubility in water | insoluble |
| log P | 0.1 |
| Acidity (pKa) | 11.5 |
| Basicity (pKb) | 5.05 |
| Magnetic susceptibility (χ) | {-7.0e-6 cm^3/mol} |
| Refractive index (nD) | 1.470 |
| Viscosity | 20 mPa·s (25 °C) |
| Dipole moment | 4.04 D |
| Pharmacology | |
| ATC code | 'V04CX' |
| Hazards | |
| GHS labelling | GHS07, GHS05 |
| Pictograms | GHS07,GHS08 |
| Signal word | Warning |
| Hazard statements | H315, H319, H335 |
| Precautionary statements | Precautionary statements: P261, P264, P271, P272, P280, P302+P352, P321, P333+P313, P362+P364, P501 |
| NFPA 704 (fire diamond) | 1-1-0 |
| Flash point | > 128 °C |
| Lethal dose or concentration | LD50 Oral - Rat: > 2,000 mg/kg |
| LD50 (median dose) | LD50 (median dose): Oral rat LD50 = 3,940 mg/kg |
| NIOSH | GV6460000 |
| REL (Recommended) | 0.05 % |
| Related compounds | |
| Related compounds |
Isocyanuric acid Cyanuric chloride Trimethoxysilane Tris(2-chloroethyl) isocyanurate Tris(2-hydroxyethyl)isocyanurate |
